Bio-Techne offers a wide range of chemogenetics products for neuroscience research: DREADDs for neuroscientists, PSEMs, uPSEMs, cell culture reagents and more.
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The bidirectional communication between nervous and immune system cells might have implications for psychiatric disorders. The cyto-chemokine system and their receptors has been described in neurons and glial cells as a major system regulating the cross-talk between the central nervous system (CNS) and...
Blood-brain barrierBrain deliveryBrain metastasesBrain tumorsChemoprotectionAlthough knowledge of molecular biology and cellular physiology has advanced at a rapid pace, much remains to be learned about delivering chemotherapy and antibodies across the blood鈥揵rain barrier (BBB) for the diagnosis and ...
It focuses on the discovery and development of small-molecule therapeutics for the treatment of ophthalmic diseases and disorders, including retinitis pigmentosa. It was founded in 2007 and is based in Cambridge, Massachusetts. L Longevica Longevica is a biotechnology that is researching mechanisms of...
Pooled Hazard Ratios (HRs) of Overall Survival Across Randomized Clinical Trials View LargeDownload Pooled HRs comparing neoadjuvant chemoimmunotherapy with neoadjuvant chemotherapy are given for all patients, by programmed cell death 1 ligand 1 (PD-L1) status, and for patients with stage III ...
1 The treatment options for these disorders are limited despite the great demand for effective therapeutics. A multitude of drugs have been developed to remedy these conditions, but few possess the efficacy and specificity necessary to achieve an effective therapeutic index. Consequently, a variety of...
Applying control inputs uniformly to all brain regions, we compute the optimal energy cost for each of the 15,129 possible transitions between cognitive topographies. We find that optimal control energy can vary by nearly tenfold across different transitions (Fig.2a–c). As a result of these ...
All patients were investigated pretreatment and at 6 months for the metabolic syndrome, as well as for related biochemical and physical parameters. RESULTS ... MA Moyad - 《European Urology》 被引量: 128发表: 2012年 The impact of rosiglitazone on cardiovascular responses and endurance during isome...
(Supplementary Fig.34b, c). Surviving mice were sacrificed at the end of treatment, and their heart tissues and blood were collected for pathological and haematological analyses, respectively. From the H&E-stained heart sections, the arranged cardiomyocytes did not have significant infiltration of ...