Treatment with Vertex and CRISPR's therapy requires that patients undergo myeloablative chemotherapy with a busulfan-based regimen followed by transplant with the modified cells back into the bone marrow, which carries a significant toxicity burden. Most side effects with exa-cel in clinical trials wer...
Treatment may involve radiation therapy, chemotherapy, immunotherapy with monoclonal antibodies, or a combination. Most people are cured or survive for many years. People who relapse are treated with stem cell transplantation. (See also Overview of Lymphoma and Hodgkin Lymphoma.) Lymphomas are cancers...
期刊名称:《Clinical Medicine Insights: Blood Disorders》 | 2013年第6期 12.Clinical Characteristics and Risk of Relapse for Patients with Stage I–II Diffuse Large B-cell Lymphoma Treated in First Line with Immunochemotherapy 机译:一线免疫放疗治疗I–II期弥漫性大B细胞淋巴瘤患者的临床特征和复发风险...
Protein Disorders Causing Bruising or Bleeding - Learn about the causes, symptoms, diagnosis & treatment from the Merck Manuals - Medical Consumer Version.
Such peptides and peptide mimetics are useful in methods for treating hematological disorders and particularly, thrombocytopenia resulting from chemotherapy, radiation therapy, or bone marrow transfusions as well as in diagnostic methods employing labeled peptides and peptide mimetics....
Lipids and disorders of lipoprotein metabolism Graham R.Bayly, inClinical Biochemistry: Metabolic and Clinical Aspects (Third Edition), 2014 CONCLUSION The principallipidspresent in the blood are cholesterol,triglyceridesandphospholipids. They are transported, in association with variousapolipoproteins, inlipo...
In most cases, excess bleeding disorders are due to a variant of hemophilia A and B, which are caused by defects in coagulation factors VIII and IX, respectively. fVIII and fIX are encoded on the X chromosome, explaining why males are affected by deficiencies of these genes with a probabilit...
A blood disease is one of four types of disease that affect the blood. The four categories of blood disease are coagulopathies...
Standard treatment of locoregional advanced NPC involves radiation therapy alone for earlier stages I and II cancer and radiation and concurrent cisplatin-based chemotherapy for later stages of the disease. Patients with stage I and II disease can usually be treated with radiotherapy alone, with ...
It is clear that risk is increased for patients treated with radiation and chemotherapy at younger ages. Radiation is associated with modest risk, whereas chemotherapy, particularly the combination of an alkylating agent and an anthracycline, carries higher risk and radiation and chemotherapy combined ...