Chemical structure and some biological properties of actinomycin. I. Chemical structure and some biological properties of actinomycinFujita, S Hiroshi
aSecondary structure of mt-tRNACyswith modifications. “p” and “OH” stand for 5′-monophosphate and 3′-hydroxy termini, respectively. Symbols for modified nucleosides are as follows: m1G 1-methylguanosine, Ψ pseudouridine, i6AN6-isopentenyladenosine, m1A 1-methyladenosine. Watson–Crick and ...
aSecondary structure of mt-tRNACyswith modifications. “p” and “OH” stand for 5′-monophosphate and 3′-hydroxy termini, respectively. Symbols for modified nucleosides are as follows: m1G 1-methylguanosine, Ψ pseudouridine, i6AN6-isopentenyladenosine, m1A 1-methyladenosine. Watson–Crick and ...
In recent years considerable progress has been made in the understanding of the structure and function of the red blood cell membrane. The protein spectrin, of high molecular weight and propensity for self-association, appears to play a major role, in concert with actin, in maintaining the shape...
In addition to the double helical structure of DNA, the genome is known to fold into a variety of noncanonical three-dimensional structures that offer unique opportunities for small molecule binding1,2. Molecules that recognize specific DNA folds that are scarce in the genome could be used to al...
The ribonucleoprotein (RNP) complex of Ebola virus (EBOV) is known to be a multiprotein/RNA structure, however, knowledge is rather limited regarding the a... A Groseth,JE Charton,M Sauerborn,... - 《Virus Research》 被引量: 107发表: 2009年 Live-cell imaging of Marburg virus-infected...
The three-dimensional structure of alpha-actinin obtained by cryoelectronmicroscopy suggests a model for Ca2+-dependent actin binding The three-dimensional structure of α-actinin from rabbit skeletal muscle was determined by cryoelectron microscopy in combination with homology modeling o... J Tang,DW...
Since the π–π* band of E-DMAB has a vibrational structure—albeit low— and Z-DMAB has none, the right value of α can be found once the subtraction leads to the complete disappearance of the vibrational structure. In our case, we applied the TEM method to the PSS obtained upon ...
c Chemical structure of RC32. d Immunoblots showing degradation of FKBP12 in Jurkat cells treated with RC32 at the indicated concentrations for 12 h. ß-Actin served as a loading control. e Immunoblots for FKBP12 protein. Jurkat cells were first treated for 3 h with bortezomib (Bor...
Herein, we report chemical tools (particularly, chemical regulators) designed based on a structure-mechanism-based concept. This design principle exemplifies that different properties (for example, metal binding, Ab interaction and ionization potentials (IPs)) of small molecules afford chemical tools ...