Chemical structure and some biological properties of actinomycin. I. Chemical structure and some biological properties of actinomycinFujita, S Hiroshi
Fucoidan is a sulfated glycan with anticoagulant properties, but its structural complexity and heterogeneity hinders understanding of its structure-activity relationship. Here, the authors synthesize a diverse library of 58 distinct fucoidans with multiple contiguous 1,2-cisglycosidic bonds and various sulf...
We used a variety of in vitro experiments to show that α-syn(gS87) does form amyloid fibrils that have a different core structure and that these fibrils seed additional aggregation and template their structure onto the newly-formed α-syn aggregates. We observed that α-syn(gS87) fibrils ...
structure display options customizing structure drawing styles drawing settings drawing styles structure display color schemes display options for implicit and explicit hydrogens displaying the label of carbon atoms error highlighting saving display options basic editing selecting a structure copy-paste and ...
The signal intensity of the protein of interest was normalized to the signal intensity of the loading control, β-actin. Prism 8 (GraphPad, San Diego, CA) was used as the statistical analysis software. To compare multiple treatments to control, one-way analysis of variance (ANOVA) was used ...
IC50of 81.3 ± 2.7 μM, equal to that of the positive control (acarbose, 72.8 ± 3.1 μM) [33]. The structure–activity relationship suggested that triterpenoids with a phenylpropanoid moiety exhibited more potent effects than those without such a unit [34]. Compound71showed ...
Polarized Cell Growth Plant cell morphology depends on polar cell expansion which may occur through two mechanisms, tip growth and diffuse growth.2,33 Tip growth involves targeted transport and vesicle fusion at the cell apex resulting in the formation of a tubular structure.2-5,34 Root hairs ...
d, WB analysis of mtDNA-encoded protein levels in MDA-MB-231 and T-47D cells stably expressing NTC or shMBD2c. Actin served as the loading control. e, MDA-MB-468 cells with stable knockout of endogenous MBD2c, were further infected with viruses expressing EV, Flag-tagged MBD2c-WT, ...
E. et al. The lipid whisker model of the structure of oxidized cell membranes. J. Biol. Chem. 283, 2385–2396 (2008). CAS PubMed Google Scholar Fritz, K. S. & Petersen, D. R. An overview of the chemistry and biology of reactive aldehydes. Free Radic. Biol. Med. 59, 85–91 ...
[2]. Polymeric opticalwaveguidestructures on polymer substrates, which require high precision in structure definition, may for instance be produced with micromolding techniques[3]. Taking advantage of the mechanical flexibility of many polymers, developments also aim at elastomeric light-emitting devices ...