Actin structure and function. Annu. Rev. Biophys. 40, 169-186.Dominguez, R., and K. C. Holmes. 2011. Actin structure and function. Annu. Rev. Biophys. 40:169-186.Dominguez R, Holmes KC. Actin structure and function. Annual review of biophysics. 2011;40:169....
The yeast Saccharomyces cerevisiae, has proven to be a powerful model organism in which to study actin function and structure-function relationships. This yeast has a single actin gene, a feature that greatly simplifies molecular-genetic and biochemical analysis of actin. Yeast actin is 88% ...
C. Actin structure and function. Annu. Rev. Biophys. 40, 169–186 (2011). Article CAS PubMed PubMed Central Google Scholar Kovar, D. R., Sirotkin, V. & Lord, M. Three's company: the fission yeast actin cytoskeleton. Trends Cell Biol. 21, 177–187 (2011). Article CAS PubMed ...
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Fig. 1.Interactions of the ADF-H domain with G-actin. (A) Atomic structure of the actin monomer with bound nucleotide (red) (PDB:3DAW). The subdomains (SD) are indicated by numbers. Red arrow shows the nucleotide binding cleft between SD2 and SD4. (B) Atomic structure of the C-term...
Higher F-act levels may be important to maintain the presence of the Golgi apparatus at branch points since actin is involved in regulating Golgi structure and function (Gu et al., 2001). Interestingly, the differences in F-act enrichment between terminating and elongating dendrites were much ...
Villin, a calcium-regulated actin-binding protein, modulates the structure and assembly of actin filaments in vitro. It is organized into three domains, the first two of which are homologous. Villin is mainly produced in epithelial cells that develop a brush border and which are responsible for ...
the precise structure of the actin arrays and their regulation by actin-associated proteins is only starting to be uncovered. Long, axially-oriented bundles of actin are abundant in the shank of pollen tubes but absent in their apices. These bundles function as tracks for the myosindependent cyto...
Structure of TccC3 HVR To understand the processing and function of a Tc toxin HVR as well as its mechanism of action, we chose the TccC3 HVR from Photorhabdus luminescens (hereafter TcHVR) for our studies. Even before the holotoxin consisting of TcA, TcB and TcC is assembled, the TcHVR...
C. Actin structure and function. Annu Rev. Biophys. 40, 169–186 (2011). Article CAS PubMed PubMed Central Google Scholar Cairns, B. R., Erdjument-Bromage, H., Tempst, P., Winston, F. & Kornberg, R. D. Two actin-related proteins are shared functional components of the chromatin...