Chemical Biology & Drug Design is a peer-reviewed scientific journal that is dedicated to the advancement of innovative science, technology and medicine with a focus on the multidisciplinary fields of chemical biology and drug design. It is the aim of Chemical Biology & Drug Design to ...
Chemical Informatics, Drug Design, Development and Therapy, International Journal of Computational Biology and Drug Design, Drug Development and Industrial Pharmacy, Journal of Molecular Graphics and Modelling, Journal of Cheminformatics, Chemoinformatics, Journal of Proteomics & Bioinformatics, Journal of Bioi...
ligands have been developed that covalently attach to their cognate RNA aptamers in vitro and in living cells. This strategy opens up new avenues for RNA imaging applications (for example, FRAP), for direct fluorescence detection of RNA pull-downs or for covalent RNA-targeted drug design. ...
Drug delivery Sustainable energy Nanomedicine Biotechnology Glycan biosynthesis Systems biology Cell culture Alternative fuels Process design 3D printing Nanomaterials Recently Published Papers New advance in application research of high-gravity process intensification technology 1 Mar 2025 Current Opinion in ...
Nature Chemical Biology thanks Yury Polikanov, Daniel Wilson and the other, anonymous, reviewer(s) for their contribution to the peer review of this work. Additional information Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional af...
Small molecules serve as scientific tools to elucidate (patho-)physiological mechanisms on a molecular level and to identify or validate drug targets. This interdisciplinary field of drug research is termed ‘chemical biology’, and has matured considerably over the past 25 years, establishing itself ...
The implication of epigenetic abnormalities in many diseases and the approval of a number of compounds that modulate specific epigenetic targets in a therapeutically relevant manner in cancer specifically confirms that some of these targets are druggable
ACS Chemical Biology provides an international forum for the rapid communication of research that broadly embraces the interface between chemistry and biology. Publisher American Chemical Society Country United States History 2006--present Website http://pubs.acs.org/journal/acbcct Impact factor 6.446 (...
Targeted protein degradation has become a notable drug development strategy, but its application has been limited by the dependence on protein-based chimeras with restricted genetic manipulation capabilities. The use of long non-coding RNAs (lncRNAs) has
and has furnished suitable start points for drug development1,2. One area that is seeing increasing interest for chemical biology and drug discovery applications is the pharmacological modulation of oxygen sensing3,4, one of the most fundamental processes in aerobic organisms5. Studying the cell’s...