而且据相关研究统计表明乳腺癌患者中有大约5%~10%的病例是由于高外显易感基因的遗传所导致的:比如与遗传性乳腺癌相关的最主要的两个肿瘤抑制基因——乳腺癌易感基因1(breast cancer susceptibility gene 1,BRCA 1)和乳腺癌易感基因2(breast
【关键词】 基因;突变;乳腺肿瘤;CHEK2CHEK2geneandbreastcancer LIAOShao guang,WANGYa jie.DepartmentofOncology,ChanghaiHos pital,SecondMilitaryMedicalUniversity,Shanghai200433,ChinaCorrespondingauthor:WANGYa jie,E mail:yajiewa0459@163.com【Abstract】 CHEK2isanimportantsusceptibilitygeneofbreastcancer.CHEK2gene...
关键词:乳腺癌;乳腺癌家族史阳性:临床特点;预后袁同学 天津医科大学硕士学位论文TheanalysisofCI皿K2genemutationandtheclinicalretrospectivestudyonfhmilialbreastcancerAbstractPartITheanalysisofCHEK2genemutationinbreastcancerfAmilies0bjective:TheaimofmestudywastoexplorethepreValence,the“hotspots”ofCHEK2.aIldwhe血er...
CHEK2 gene is known as a tumor suppressor gene in breast cancer (BC), which plays a role in DNA repair. The germ line mutations in CEHK2 have been associated with different types of cancer. The present study was aimed at studying the association between CHEK2 mutations and BC. Peripheral...
CHEK2基因突变初探及家族性乳腺癌临床回顾性研究
[6] Yadav S, Couch FJ: Germline genetic testing for breast cancer risk: The past, present, and future. Am Soc Clin Oncol Ed Book 39:61-74, 2019 [7] Palmer JR, Polley EC, Hu C, et al: Contribution of ...
Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors. This nuclear protein...
to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, ...
to restore survival after DNA damage. Mutations in this gene have been linked with Li-Fraumeni syndrome, a highly penetrant familial cancer phenotype usually associated with inherited mutations in TP53. Also, mutations in this gene are thought to confer a predisposition to sarcomas, breast cancer, ...
常用塑料耗材: 吸头 离心管 核酸纯化柱