Clinical trials studying neoadjuvant and adjuvant therapy around prostatectomy for patients with high‐risk prostate cancer have faced multiple challenges. Patients who have a very good response to neoadjuvant therapy may not wish to continue to adjuvant treatment, and prostate‐specific antigen–based ...
(eg,phase3trialsfordrugregistration),moststudiesarenotintendedtobeexactrep-licasofprevioustrials.However,evenifdifferentclinicaltrialspro-ducesimilarresults,onestillcannotassumethatthoseresultswillbeobtainedinone’spractice.Restrictiveenrollmentcriteria,pub-licationbias,biologicalvariability,andinadequateexperimentalde-...
Tips and Tools to Overcome DE&I Challenges in Clinical Trials: Navigating FDA's draft guidance and heightened diversity recommendations Applied Clinical TrialsPachter, Ashley
Challenges in Conducting Clinical Trials for Preeclampsia doi:10.1007/s11906-023-01276-yCurrent Hypertension ReportsBank, T. CarolineKline, DianaCostantine, Maged M.
there is an abysmal 90% failure rate for novel drugs in clinical trials, meaning only 1 out of every 10 drug candidates. There is no question the novel drugs that manage to work their way through to market make a critical impact, but those life-changing – and often life-saving –...
What is the importance of having diversity in clinical trials? I think it is extremely important. I think this study shows that beyond racial diversity, economic diversity is also important, making sure that people who come from less wealthy backgrounds and more vulnerable areas [who] also may ...
Electronic Patient-Reported Outcomes (ePRO) are digital tools intended to collect data directly from patients participating in clinical trials. It means the patient-reported information about their symptoms, experiences, and overall well-being can be collected in real-time and done accurately. The ePR...
Most sponsors face roadblocks when conducting clinical trials - don't get stuck for any reason. Our team helps organizations circumvent clinical trial challenges & get back on track.
Review Article Challenges in launching multinational oncology clinical trials in India Kamal S. Saini, Gaurav Agarwal1, Ramesh Jagannathan2, Otto Metzger‑Filho3, Monika L. Saini4, Khurshid Mistry5, Raghib Ali6, Sudeep Gupta7 Abstract In the recent past, there has been a...
BACKGROUND: Progress in clinical medicine relies on the willingness of patients to take part in experimental clinical trials, particularly randomized contr... B Djulbegovic - 《Cancer Control Journal of the Moffitt Cancer Center》 被引量: 134发表: 2009年 The Use of Equipoise in Clinical Trials ...