In clinical development of a test treatment, clinical trials are usually conducted to collect data for evaluation of safety and efficacy of the test treatment under investigation. To provide accurate and reliable assessment, well-controlled clinical trials under valid study designs are necessarily ...
- 《Contemporary Clinical Trials》 被引量: 67发表: 2013年 Issues in the design of a randomized noninferiority clinical trial of telemental health psychotherapy for rural combat veterans with PTSD This methodological article provides a description of the design, methods, and rationale of the first ...
SeveralspecialissuesariseinrelationtoclinicaltrialsoftherapyforsexuallytransmitteddiseasesTheseissuesincludethedesirabilityofincludingadolescentsandbothpregnantandnonpregnantwomeninthetrial,theuseofunapprovedcontrolregimens,problemswithantimicrobialsusceptibilitytestingduetoinadequatemethodologyandtheneedforprompttreatment,theneedtoas...
A. (1998). Clinical trials in developing countries: Scientific and ethical issues. Medical Journal of Australia, 169(10), 545-548.Studdert D, Brennan T. Clinical trials in developing countries: scientific and ethical issues. Med J Australia 1998:169;545–548....
Methodologic Issues in Clinical TrialsCareful planning of clinical trials is essential to achieve valid results. If the trial is randomized and well designed with respect to timing, choice of study population, completeness of follow-up,...
Naturally, the Bio Specimen Sample Logistics service can be used in combination with other DHL services, to create a solution that serves your exact delivery and collection needs. DHL Customer Solution & Innovation • Clinical Trials • 9 The Bio Specimen Sample Logistics offering includes: •...
various aspects of clinical trials was assembled in May 2000, Participants described and evaluated the mechanisms by which clinical trials are monitored, focusing on adverse event reporting and the processes by which various parties with oversight responsibilities interact in the course of these trials....
In the US, large neonatal networks have been formed so that large databases can be created and large multi-center trials can be performed. The practical issues associated with these network studies is the center to center variability in patient care may dwarf the beneficial effect of the ...
I pledge to pursue the practice of surgery with honesty and to place the welfare and the rights of my patient above all else. I promise to deal with each patient as I would wish to be dealt with if I was in the patient’ s position and I will respect the patient’ s autonomy and ...
Small Clinical Trials Issues and Challenges ( 2001 ) 0期:目的是在满足一定的统计学要求的前提下,在有限的样本量(通常不超过20)、有限的时间内(每个患者的治疗期常不超过数周),初步判断一个研究药物是否有效、某个剂量是否有效,是否应继续开发下去,附带看一下某些疗效判断方法是否可行。从目的角度,0期研究也是...