Alright, now moving on to pharmacology. cGMP-mediated smooth muscle vasodilators are subdivided into two main groups:antianginal medications, which are used to treat anginal pain, when oxygen delivery to the heart is inadequate for normal heart function; andantihypertensive medications, which are us...
sGC stimulators are a class of small molecule allosteric modulators, which stimulate cGMP production independently of NO but also act in synergy with NO. Evidence to date suggests that sGC stimulators may be balanced vasodilators, meaning that they elicit vasorelaxation in both the arterial and ...