001治疗急性冠脉综合征(ACS)的2期CHI-SQUARE(HDL浸剂可大大加快动脉粥样硬 化的消退?)研究。 CER-001是一种新型重组人载脂蛋白A-Ⅰ(ApoA-I)复合物。它模拟自然新生HDL(或称 为前β-HDL)的结构和功能,也被认为可预防动脉粥样硬化。研究人员希望CER-001通过 促进血管壁胆固醇的去除而将进一步降低高危患者的心血...
T/HCER 001-2019 适用范围 1 范围本标准规定了再生工业级氢氧化铬的原料与工艺、质量要求、试验方法、检验规则、标志、包装、运输和贮存。本标准适用于以电镀含铬废液、毛皮鞣制及制品加工产生的含铬废水与处理污泥为主要原料,经预处理、还原、沉淀、压滤等工序制成的含有一定杂质的粉状工业级氢氧化铬,主要用于制备...
CER-001 is a novel engineered HDL-mimetic comprised of recombinant human apoA-I and phospholipids that was designed to mimic the beneficial properties of nascent pre-β HDL. In this study, we have evaluated the capacity of CER-001 to perform reverse lipid transport in single dose studies as ...
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O—N-脂酰鞘氨醇(Cer)001细胞膜产生N-脂酰鞘氨醇(Cer)324激活口细胞口凋亡凋亡酶凋亡酶线粒体激活因子N脂酰鞘氨醇(Cer)在肿瘤细胞凋亡调控中起重要作用。它能通过线粒体的调节,促进凋亡酶激活因子的释放,激活细胞内的凋亡酶,从而使肿瘤细胞凋亡,调控过程如图所示,下列叙述错误的是( ) A. 过程①的结合...
Infusion of HDL mimetic CER-001 increases plasma apoA-I concentration and plasma cholesterol efflux capacity. Our data support the concept that CER-001 targets plaque regions in patients, which correlates with plaque contrast enhancement. These clinical findings may also guide future nanomedicine develop...
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Conclusion In patients with genetically determined very low HDL-cholesterol, 24 weeks of treatment with HDL mimetic CER-001 did not reduce carotid vessel wall dimensions or arterial wall inflammation, compared with placebo. 展开 关键词: CER-001 Familial hypoalphalipoproteinemia HDL MRI PET/CT ...
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