memory T细胞往下细分，可以分成central memory T cell和effector memory T cell，前者主要在淋巴器官里和...
Central memory T cells (TCM cells) express the lymph node homing receptors CD62L and CCR7, have poor effector function and proliferate efficiently upon antigenic stimulation. Effector memory T cells (TEM cells) do not express CCR7, are mostly CD62L negative and therefore are excluded from lymph...
A total of 40% of CCR7− re-directed T cells had an effector memory phenotype and 5% a central memory phenotype. Based on CCR7 cell sorting, effector and memory CAR-positive T cells were separated and CCR7+ memory cells demonstrated after antigen-specific re-stimulation downregulation of CCR7...
Immunological memory is an important characteristic of adaptive immune response and elucidation of its cellular basis is critical for vaccine exploration and disease prevention. Recent studies have shown that memory T cells could be divided into central memory T cells and effector memory T cells, which...
A total of 40% of CCR7(-) re-directed T cells had an effector memory phenotype and 5% a central memory phenotype. Based on CCR7 cell sorting, effector and memory CAR-positive T cells were separated and CCR7(+) memory cells demonstrated after antigen-specific re-stimulation downregulation of ...
货号:17865 名称:EasySep™ 人中央和效应记忆CD4+T细胞分选试剂盒 品牌:STEMCELL 规格:For processing 1×10^9 cells 产品描述:Immunomagnetic cell isolation kit using particle release technology 购买数量: 立即购买 产品信息 This kit isolates human CD62L+CD45RO+ and CD62L-CD45RO+ memory CD4+ T cell...
Roberts AD, Ely KH, Woodland DL (2005) Differential contributions of central and effector memory T cells to recall responses . J Exp Med 202 : 123–133doi: 10.1084/jem.20050137Roberts AD, Ely KH, Woodland DL. Differential contributions of central and effector memo...
Central memory T cells TEM: Effector memory T cells CSCs: Tumor stem cells EPCs: Endothelial progenitor cells MB: Medulloblastoma PFA: Posterior fossa A TM: Transmembrane iC9: Inducible caspase 9 PDOX: Patient derived orthotopic xenograft
Definition Memory CD4 T cells can be divided into central memory (T CM ) and effector memory (T EM ) subsets, which are endowed with different homing and proliferative capacities as well as distinct effector functions (Sallusto et al. 1999 ). T CM cells can directly home to secondary lymph...
Memory T cells can be classified as central memory (T CM, CD45RA negCCR7 +), effector memory (T EM, CD45RA negCCR7 neg), and terminally differentiated cells (T TD, CD45RA +CCR7 neg) with different homing and effector capacities. In 101 healthy subjects aged from 5 to 96 years, dis...