provided with a new direction and thrust from these developments. AI and ML has been applied to both ligand-based and structure-based drug discovery and design of CNS therapeutics. In this review, we have summarised the general aspects of AI and ML from the perspective of drug discovery follow...
Age distribution of igneous rocks in the Central European Volcanic Province. The data of this work are amended by literature data (except for K–Ar data; Abratis et al.2007; Aziz et al.2010; Büchner et al.2015; Fekiacova et al.2007; Ghobadi et al.2021; Gregor2003; Harangi et al.2...
Article Refining Species Traits in a Dynamic Vegetation Model to Project the Impacts of Climate Change on Tropical Trees in Central Africa Marie Dury 1,*, Lenni Mertens 1,2, Adeline Fayolle 3, Hans Verbeeck 4 , Alain Hambuckers 2 and Louis François 1 1 Modélisation du Climat et des ...
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Cyanobacteria from the genus Microcystis can form large mucilaginous colonies with attached heterotrophic bacteria—their microbiome. However, the nature of the relationship between Microcystis and its microbiome remains unclear. Is it a long-term, evolu
Heterotrimeric G proteins are fundamental signaling proteins composed of three subunits, Gα and a Gβγ dimer. The role of Gα as a molecular switch is critical for transmitting and amplifying intracellular signaling cascades initiated by an activated G
plotting support for bipartitions of interest after the stepwise removal of the 6000 fastest evolving sites (top) and 6000 most heterotachous sites (bottom) until all sites are removed from each dataset (dataset A on the left and dataset B on the right). Non-parametric bootstrap support (n...
on a daily basis, the cause often remains unknown and cannot be explained by hormonal and testicular disorders and genetic factors such as Klinefelter syndrome (XXY), rearrangements in the AZF gene, and mutations in other infertility related genes, such as AR, CFTR, NR5A1,...
The anthropogenic salinisation of rivers (especially the strong salinity that is associated with the discharge of salty mine waters, but also with the agents that are used to de-ice roads) and its impact on freshwater biota illustrates the consequences of climate change. The consequences of ...
10. Biswas PS, Banerjee K, Kinchington PR, Rouse BT: Involvement of IL-6 in the paracrine production of VEGF in ocular HSV-1 infection. Exp Eye Res 2006, 82:46-54. 11. Arbiser JL: Implications of Epstein-Barr Virus (EBV)-induced carcinogenesis on cutaneous inflammation and carcinogene...