Cellular theories of aging propose that human aging is the result of cellular aging, whereby an increasing proportion of cells reach senescence, a terminal stage at which cells will cease to divide. This will limit the body's ability to regenerate and to respond to injury or stress. This ...
The process of cell growth and division into two identical daughter cells occurs in a series of regulated steps called the cell cycle. There are four main stages that cells pass through during the cell cycle: (1) “G1” also called... Diggs, J. (2008). Cellular Theory of Aging. In: ...
细胞死亡理论( cellular aging theory) 4.基因理论( gene theor…www.nhu.edu.tw|基于6个网页 2. 细胞老化理论 细胞老化理论(cellular aging theory) (p. 106)细胞老化理论提出,老化会使细胞的复制过程延缓,Hayflick以及Moorehead(1961) …www.ppt2txt.com|基于3个网页 3. 细胞老化論 ‧细胞老化論(...
Harman, in 1956, proposed the “free radical theory of aging,” which argued that ROS derived from metabolism were the primary cause of aging [7]. Since then, several publications have reported the deleterious effects of ROS on aging [8, 9]. However, recent studies on long-lived models an...
Aging is one of the unique features in all organisms. The impaired functional capacity of many systems characterizes aging. When such impairments occur in the brain, the susceptibility to neurodegenerative diseases amplifies considerably. The free radical theory of aging posits that the functional impair...
The current theory of coacervation posits that phase separation is driven by forces generated by weak electrostatic and hydrophobic interactions between amino acid side chains and interacting biomolecules. In this study, we demonstrated senescence-associated formation of protein condensates in the nuclei of...
Cellular aging is difficult to study in individuals with natural infection, given the diversity of symptom duration and clinical presentation, and the high interference of aging-related processes with host and environmental factors. To address this challenge, we took advantage of the controlled human ...
The latter part of the 20th century was a period characterized by a fundamental transition in scholarship on activity and the aging process. Theory emphasi... Johnson,J Kimberly,Mutchler,... - 《Gerontologist》 被引量: 34发表: 2014年 Aging in Lebanon: Challenges and Opportunities This spotlight...
© 2019 Springer Science+Business Media, LLC, part of Springer Nature About this entry Cite this entry Toescu, E.C. (2019). Cellular Theory of Aging. In: Gellman, M. (eds) Encyclopedia of Behavioral Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-6439-6_447-...
A. Experimental evidence of the relationship between aging and oxygen want; in search of a theory of aging. Ergonomics, 1963, 6, 339–366. CrossRef Medvedev, ZH. A. Aging at the molecular level and some speculations concerning maintaining the functioning of systems for replicating specific ...