Biochemistry The cellular nucleic acid binding protein in aging and disease UNIVERSITY OF KENTUCKY M. Paul Murphy WebbRobin LThe ZNF9 gene on chromosome 3 encodes the cellular nucleic acid binding protein (CNBP), a ubiquitously expressed, 177 amino acid (≈19.5kDa) protein that is highly ...
1) Cellular nucleic acid-binding protein (CNBP) 细胞核酸结合蛋白(CNBP) 2) Cellular retinol-binding protein-Ⅰ(CRBP-Ⅰ) 细胞内视黄酸结合蛋白- 3) CRABP 细胞内维A酸结合蛋白 4) Hepatocyte binding protein 肝细胞结合蛋白 5) intracellular binding protein (ICBP) ...
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A zinc-requiring purine strand binding activity was identified as cellular nucleic acid binding protein (CNBP), a protein previously implicated in the regulation of sterol responsive genes. Two forms of CNBP differed in their relative binding to the CT- or sterol-response elements. CNBP was shown...
Human Cellular Nucleic Acid-Binding Protein Zn[sup 2+] Fingers Support Replication of Human Immunodeficiency Virus Type 1 When They Are Substituted in the ... .Human cellular nucleic acid-binding protein Zn2+fingers supportreplication of humanimmunodeficiency virus type1whenthey are substitutedinthe ...
We cloned and sequenced the cDNAs which code for rat cellular nucleic acid binding protein (CNBP). In-frame insertion/deletion differences were found among the clones at two sites in the open reading frame, suggesting alternative splicing of the message or the presence of multiple genes which cod...
networks to identify nucleic-acid-binding residues on proteins23. Zhang et al.24presented DeepDISOBind, a deep multi-task architecture that accurately predicts DNA-, RNA- and protein-binding regions from protein sequences. Most recently, Lam et al. introduced NucleicNet, a deep learning model ...
a Schematic of SUN2 protein trimer spanning the NE and linking between the nuclear lamina and nesprins71. MS detected four mechano-responsive phosphorylation sites within the lamin-binding domain of SUN2. ONM = outer nuclear membrane; INM = inner nuclear membrane. b Amino acid ...
The RNA recognition motif (RRM), also referred to as RNA-binding domain (RBD) or ribonucleoprotein domain (RNP), is the most abundant nucleic acid-binding motif in the human genome (Clery et al., 2008). RRMs are found in a wide variety of RNA and ssDNA-binding proteins. RRMs may be ...
et al. Predicting intrinsic disorder from amino acid sequence. Proteins: Struct. Function Bioinformat. 53 (Suppl. 6), 566–572 (2003). Article CAS Google Scholar Ishida, T. & Kinoshita, K. PrDOS: prediction of disordered protein regions from amino acid sequence. Nucleic Acids Res. 35, W...