Lipogenesis, the process of fatty acid and subsequent triglyceride synthesis, occurs primarily in the liver and adipose tissue [11,12]. This process is highly sensitive to dietary changes. A carbohydrate-rich diet stimulates lipogenesis in the liver and adipose tissue, leading to elevated postprandial...
Kyoto Encyclopedia of Genes and Genomes (KEGG) and Gene Ontology (GO) pathway enrichment analysis were performed using the “clusterProfiler” R package; a Benjamini–Hochberg correctedP-value < 0.05 was considered significant [24]. For GO pathway enrichment, only “Biological Process” GO term...
coli TRN-PPN GPEA analysis we observe only 5 terms for carbohydrate and alcohol metabolic processes. Figure 6 E. coliBiological process GPEA analysis of the network interfaces.A) GRN-PPN 137 terms (fdr≤0.01), B) GRN-TRN 28 terms (fdr≤0.01), C) TRN-PPN 5 terms (fdr ≤ 0.01). ...
Among them, autophagy as a high conserved cellular process is thought to be critical in affecting cell survival. Hepatocytes are dependent on basal autophagy to supple energy because of the high biosynthetic activity and carbohydrate storage. Furthermore, the activation of autophagy happened in liver ...
Ketone bodies also modulate the NLRP3 inflammasome. β-Hydroxybutyrate (BHB) is a ketone produced in the liver that can be used as an energy source in animals on a low-carbohydrate diet (the so-called ketogenic diet) or under conditions of nutrient deprivation. BHB efficiently blocks the NLRP...
During this process, NADP+ is reduced to NADPH which is a critical cofactor for many enzymatic reactions in lipid biosynthesis [32]. Diatoms do not possess starch-forming enzymes, but store fixed carbon as a complex, soluble carbohydrate called chrysolaminarin (β-1, 3-glucan) in vacuoles. ...
B participates in many metabolic and physiological processes in higher plants, including cell wall synthesis and lignification, cell wall structural maintenance, phenol metabolism, sugar transport, and carbohydrate metabolism [10]. B is able to crosslink with two rhamnogalacturonan-II (RG-II) pectic...
During this process, NADP+ is reduced to NADPH which is a critical cofactor for many enzymatic reactions in lipid biosynthesis [32]. Diatoms do not possess starch-forming enzymes, but store fixed carbon as a complex, soluble carbohydrate called chrysolaminarin (β-1, 3-glucan) in vacuoles. ...
T cell metabolism is dynamic and highly regulated. While the intrinsic metabolic programs of T cell subsets are integral to their distinct differentiation and functional patterns, the ability of cells to acquire nutrients and cope with hostile microenvir
Therefore, BGLs do not generally possess Carbohydrate Binding Modules (CBMs) like the EGs and CBHs. Rather they encode domains like the Fn3 domain which are known to participate in maintaining structural stability of the enzyme and to ensure proper positioning of the substrate. The cata- lytic ...