ASCs originate during ontogenesis and remain in a marginal area in a quiescent state as the local stimuli induce their cycle recruitment and migration. In fact, niche microenvironment, with physical contact and chemical dialogue among SCs, stromal cells and matrix, induce ASCs differentiation and ...
In the quiescent telogen stage, McSCs displayed the compact oval or bipolar shape of undifferentiated melanocytes. However, they showed marked changes during early anagen (anagen II), when TA cells emerge in this HG compartment4,5,6, with all melanocytes in the HG developing a dendritic appea...
et al. Exercise rejuvenates quiescent skeletal muscle stem cells in old mice through restoration of cyclin D1. Nat. Metab. 2, 307–317 (2020). Article CAS Google Scholar Chakkalakal, J. V., Jones, K. M., Basson, M. A. & Brack, A. S. The aged niche disrupts muscle stem cell ...
However, the molecular and biological events that take place within the precancer during this quiescent stage are not yet fully understood. The main purpose of this review is to evaluate the data from literature as well as my own findings regarding the preneoplastic and their progression into ...
Palmer TD, Ray J, Gage FH: FGF-2-responsive neuronal progenitors reside in proliferative and quiescent regions of the adult rodent brain. Mol Cell Neurosci. 1995, 6: 474-486. 10.1006/mcne.1995.1035. Article CAS PubMed Google Scholar Nunes MC, Roy NS, Keyoung HM, Goodman RR, McKhann G...
Generation of Quiescent Cardiac Fibroblasts From Human Induced Pluripotent Stem Cells for In Vitro Modeling of Cardiac Fibrosis induced pluripotent stem cellstranscriptomeRationale: Activated fibroblasts are the major cell type that secretes excessive extracellular matrix in response to ... Zhang, HadTian,...
(4~5 days postfertilization) by destroying the source blastocyst or by harvesting later stage (3 month gestational age or less) tissues. hESCs are the first stem cells to have been applied in research applications, especially, they are still commonly used in the clinical trials at present (...
In Terence Kin Wah Lee’ s study, CD24+ cells were more quiescent, with a greater ability to form tumors in Non-obese diabetic (NOD) /Severe combined immune deficient (SCID) mice, and an ability to self-renew, differentiate, and metastasize, especially upregulated in residual resistant ...
In the context of tumor dormancy, this method can be combined with Hoechst-Pyronin Y staining to distinguish cells that are in a quiescent G0 state44,45. Furthermore, several groups have reported the use of cell division dyes, such as DiD46 or CellTrace Violet19, to monitor cell ...
The frequency of quiescent stage of CD133+ cells in total aspirated human bone marrow mononuclear cells was around 1–2%51, however, it has been wildly reported that the CD133+ positive cell in peripheral blood maintains cells proliferation and regenerative potentials52,53. Accumulation of ...