▸Membranes create insides and outsides (i.e., internal microenvironments) - Enables regulation of the local chemical environment (e.g., homeostasis), regulated movement across membrane; - Achieved via a plasMa membrane and sometimes cell walls; (a) nasal sinus cells, (b) onion cells, (c...
Fig. 1: Reconfigurable DNA rafts working on lipid membranes. a, Schematic of the reconfigurable DNA nanorafts interfacing with a synthetic cell, assisted by biogenic pores, OmpF. b, Schematic of the reversible conformation changes of the DNA origami-based nanoraft from the s-DR to e-DR state...
As known from erythrocyte studies (Zilker et al., 1992), cell membranes exhibit thermally induced undulations, leading to repulsive forces. These undulation forces, as discussed by Seifert and Lipowsky (1990), have been shown experimentally to substantially reduce the van der Waals attraction and ...
Most patients with prostate cancer inevitably progress to castration-resistant prostate cancer (CRPC), at which stage chemotherapeutics like docetaxel become the first-line treatment. However, chemotherapy resistance typically develops after an initial p
Cholesterol mobilization regulates dendritic cell maturation and the immunogenic response to cancer To mature, dendritic cells collect and synthesize cholesterol to construct lipid nanodomains on their membranes. Obstructing this process impairs their ability to prime T cells. ...
Previous work from our laboratory demonstrated nanopore formation in cell membranes following exposure to nanosecond pulsed electric fields (nsPEF). We observed differences in sensitivity to nsPEF in both acute membrane injury and 24 h lethality across multiple cells lines. Based on these data, we ...
The calcium-dependent, homophilic cell adhesion protein N-cadherin (encoded by the geneCadherin-2) is diffusely distributed on the basolateral plasma membranes of retinal stem cells and progenitors in the CMZ and adjacent ciliary epithelium (Fig.1J), similar to the distribution of N-cadherin on ...
CELL STRUCTURE AND FUNCTIONS Draw and label the parts of the cell membrane. The Plasma Membrane. The Plasma Membrane Biology Fall 2017. Movement of particles across the cell membrane without using energy Prokaryotes vs Eukaryotes The Plasma (Cell) Membrane Two Basic Cell Types: Prokaryoti...
Double cross-linked 3D layered PBI proton exchange membranes for stable fuel cell performance above 200 °C Phosphoric acid (PA) doped proton exchange membranes (PEMs) often degrade above 200 °C due to membrane creeping, PA dehydration, and condensation. Here, the authors introduce gel-state...
Different mechanisms have been proposed to explain perforin-biased effects on target cell membranes. Surface cathepsin B in lytic granules is thought to degrade and inactivate perforin, thereby protecting CTLs from autolysis9. However, this hypothesis has not been proven in cathepsin B-deficient CTLs...