Facilitating the movement of molecules and ions across the cell membrane constitutes a pivotal and intricate process. This process not only maintains the cellular environment but also fosters interactions with the surroundings. Its significance lies in upholding homeostasis, bolstering cellular activities, ...
A membrane-bound cell is surrounded by a membrane known as the cell membrane, also referred to as the plasma membrane. The plasma membrane separates the internal components of a cell and the environment. Eukaryotic cells contain specialized organelles that are called membrane bound organelles. These...
1. Neurons in the nucleus of the diagonal band of Broca (nDBB) and ventral portion of the medial septum (MS) were studied using intracellular recording and single-electrode voltage clamp (SEVC) techniques in an in vitro brain slice preparation. Cell types could be operationally divided into ...
Prescott SA, De Koninck Y (2002) Four cell types with distinctive membrane properties and morphologies in lamina I of the spinal dorsal horn of the adult rat. J Physiol 539:817-836. MedlinePrescott SA, De Koninck Y.(2002), Four cell types with distinctive membrane properties and morphologies...
The GLP-1 receptor, one of the most successful drug targets for the treatment of type 2 diabetes and obesity, is known to engage multiple intracellular signaling proteins. However, it remains less explored how the receptor interacts with proteins on the cell membrane. Here, we present a ligand...
To make fuel cells economically competitive, there are many practical problems to be overcome as well. Water management remains a key problem in Proton Exchange Membrane Fuel Cells (PEMFCs). Not enough water and the polymer loses its ability to conduct protons across the cell, too much and the...
The cell membrane protects and balances many aspects of the cell, and can cause different diseases when improperly functioning. Identify types of genetic diseases, infectious diseases, and those with unknown causes that involve cell membranes.
To address this gap, we map LAMIN B1 occupancy across twelve human cell types encompassing pluripotent stem cells, intermediate progenitors, and differentiated cells from all three germ layers. Integrative analyses of this atlas with gene expression and repressive histone modification maps reveal that la...
It has been recently studied that the highly reactive surface of cadmium telluride quantum dots aggravates extensive reaction with oxygen thus causing potential damage to the cell membrane, mitochondria, and cell nucleus (Marco et al., 2007). Thus, it cannot be concluded that the resulting ...
We recently found that several of our observations in C. elegans also hold true in mammalian cells. In particular, AdipoR2 is essential in maintaining membrane fluidity in HEK293 cells challenged with the SFA palmitic acid (PA; 16:0); it can also maintain cell-membrane homeostasis nonautonomous...