The development of single-cell and spatial transcriptomics methods was instrumental in the conception of the Human Cell Atlas initiative, which aims to generate an integrated map of all cells across the human body. These technology advances are bringing
Download references Acknowledgements This work was supported by the Stand Up To Cancer (SU2C) Convergence 2.0 Grant (M.S., A.C.C., C.S.M.), a collaboration by SU2C and the Society for Immunotherapy of Cancer; the SU2C Phillip A. Sharp Award for Innovation in Collaboration (grant numbe...
Kinases are conserved during evolution. Orthologs with 'kinase domains' (so-called protein kinase-like folds; PKL) are found in all three domains of life, [1]. Interestingly, comparing the 'kinomes' from nematodes, insects, and vertebrates a surprising number of kinases are shared. In eukaryot...
Versions Notes Abstract This paper analyses the impact of the diatomaceous earth/peat (DEP; 3:1) microbial carrier on changes in the bacterial microbiome and the development of biofilm in the anaerobic digestion (AD) of confectionery waste, combined with digested sewage sludge as inoculum. The phy...
Versions Notes Abstract Neurogenesis is significantly reduced in Alzheimer’s disease (AD) and is a potential therapeutic target. Contrary to humans, a zebrafish can regenerate its diseased brain, and thus is ideal for studying neurogenesis. To compare the AD-related molecular pathways between humans...
Unit 6 Notes: Cell Basics Advertisements Cell Reproduction Chromosomes Mitosis Meiosis Chromosomes Mitosis Meiosis. Topic: Variation L1: Genetic Variation Learning Objectives: 1.Describe the two types of variation, genetic and environmental. 2.Explain how genetic information....
Furthermore, the coordinating efforts in CLO developments with other biomedical ontologies such as those in the OBO Foundry will promote broader integration of cell line information with other domains in life science. Conclusions Capabilities embedded within the CLO’s structure facilitate knowledge ...
life [33]. In an experiment, more than 300 different factors have been recognized around gold NPs (AuNPs) [34]. Using LC–MS/MS and ELISA analyses, about 288 serum proteins were detected around AuNPs and interestingly 93% of PC components are generated by 80 proteins [35]. Based on ...
Life Technolgies.), is a commercially available vector which directs the cell surface display of proteins on mammalian cell utilizes the membrane domain of cell surface platelet derived growth factor receptor PDGFR. Proteins expressed from the pDISPLAY vector are anchored to the plasma membrane of ...
Predivac bases its prediction on the concept of specificity-determining residues. The performance of the method was assessed both for high-affinity HLA class II peptide binding and CD4+ T-cell epitope prediction. In terms of epitope prediction, Predivac outperformed three available pan-specific ...