Natural killer (NK) cells represent the primary innate immune cell type. They recognize and kill cancer by detecting downregulation of MHC class I on tumor cells and/or by detecting upregulation of ligands on tumor cells that bind to activating receptors on NK cells. NK cells are commonly iden...
The immune system protects the host through a coordinated response of innate and adaptive immune cells. Defining each of these subsets can be a daunting task. Bio-Techne is here to help you visualize human immune cell subsets of interest with our Cell Markers Guide for Human Immune Cell Charact...
Human Immune Cell Marker Guide for IHC This guide elucidates key cell and functional state markers for immune cells in humans, optimized for immunohistochemistry. Mouse Immune Cell Marker Guide for IHC This guide shows the key cell and functional state markers for immune cells in mice, like CD86...
Interactions between tumor cells and immune cells are a core focus of cancer research. A comprehensive analysis of immune cell infiltration in tumors can provide a deeper understanding of the mechanisms underlying tumor survival, and may lead to potential targets for cancer treatment. Cancer is a sy...
The objective of this review is to survey the current progress in the field of cell-type identification, starting with the Human Cell Atlas project, which aims to sequence every cell in the human body, to molecular marker databases for individual cell types and other sources that address cell-...
Haematopoietic stem cells (HSCs) support maintenance of the haematopoietic and immune systems throughout the life of vertebrates, and are the therapeutic component of bone marrow transplants. Understanding native specification of HSCs, to uncover key sig
FEBS Open Bio is an open access journal for the rapid publication of research articles across the molecular and cellular life sciences. The journal’s rigorous peer review process focusses on the technical and ethical quality of papers, rather than obje
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Human T cells coordinate adaptive immunity in diverse anatomic compartments through production of cytokines and effector molecules, but it is unclear how tissue site influences T cell persistence and function. Here, we use single cell RNA-sequencing (scR
YTHDF1 boosts the lactate accumulation to potentiate cervical cancer cells immune escape Jing Xiong ,Ling He &Shujuan Sun Article 16 November 2024|Open Access FATS inhibits the Wnt pathway and induces apoptosis through degradation of MYH9 and enhances sensitivity to paclitaxel in breast cancer ...