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在Cancer Cell杂志上发表了一项重要研究成果:他们提出了一个单细胞系统药理学分析框架,利用来自人类细胞图谱HCA的目前最大的人类骨髓单细胞RNA测序数据集,更精确地分了人类B细胞发育阶段,发现了在白血病治疗中有望克服常规化疗药物抗性的组合...
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2024年7月22日,国家儿童医学中心(上海)/上海交通大学医学院附属上海儿童医学中心段才闻与海南医科大学陈国强等在Nature Cell Biology发表题为Trafficking circuit of CD8+ T cells between the intestine and bone marrow governs antitumour i...
Cancer Cell——[31.743] 微生物组存在于粘膜表面以及不同癌症的低生物量生态系统中,多组学大数据分析有助于理解微生物组与癌症的关系; 癌症相关的微生物(细菌、病毒、真菌、寄生虫)及群落失调,可能促进癌症的发生发展; 其机制包括:接触依赖性互作(与宿主细胞直接互作)、非接触依赖性互作(从远端释放促癌分子和外膜...
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and Robert G. Webster Endowed Chair in Immunology. His research focuses on mechanisms of immune signaling and metabolism, in particular how mTOR and other signaling pathways interplay with metabolic programs in T cell fate decisions and dendritic cell biology. Among the highlights of the work, his...
Questions on Cell signaling 4. Which one of the following statements about receptor – enzyme is FALSE? (CSIR Life sciences,June 2016) 1. A receptor – enzyme has an extracellular ligand binding domain, a transmembrane domain and an intracellular catalytic (enzyme) domain. 2. Many types of re...
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