Genomic DNA from these cell lines were analyzed with short tandem repeat probes for authentication (LabCorp, Burlington, NC, USA). Cells were cultured in a 5% CO2 incubator in Dullbeco’s modified Eagle’s medium (DMEM, Gibco/Thermofisher, Waltham, MA, USA) supplemented with 10% fetal ...
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Alternatively, an active survival signal may provide advantage for cells to survive through the G2/M cell cycle checkpoint, properly repair and further expand (see below). It is well known that DNA DSBs are normally generated in response to DNA damaging agents (e.g. ionizing irradiation, ...