Cell Mol Gastroenterol Hepatol. 2022;14(3):609–24. Article PubMed PubMed Central Google Scholar Gouw AM, Margulis K, Liu NS, Raman SJ, Mancuso A, Toal GG, et al. The myc oncogene cooperates with sterol-regulated element-binding protein to regulate lipogenesis essential for neoplastic ...
Cell. Mol. Gastroenterol. Hepatol. 13, 1741–1756 (2022). Article CAS PubMed PubMed Central Google Scholar Bloom, S. I., Islam, M. T., Lesniewski, L. A. & Donato, A. J. Mechanisms and consequences of endothelial cell senescence. Nat. Rev. Cardiol. 20, 38–51 (2023). Article...
Cell Mol. Gastroenterol. Hepatol. 5, 539–548 (2018). Article PubMed PubMed Central Google Scholar Wagner, A., Regev, A. & Yosef, N. Revealing the vectors of cellular identity with single-cell genomics. Nat. Biotechnol. 34, 1145–1160 (2016). Article CAS PubMed PubMed Central Google...
SalminenS,ColladoMC,EndoA,HillC,LebeerS,QuigleyEMM,etal.The International Scientific Association of Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of postbiotics.Nat Rev Gastroenterol Hepatol.2021;18:649–67. RadAH,Aghebati-MalekiL,KafilHS,AbbasiA.Molecular mechanis...
Relatively small quantities of other lipotoxic lipid species may exert a disproportionate impact in the development of NASH. Lipidomic analyses of human livers with NAFLD reported that levels of free (unesterified) cholesterol (FC) were increased in NASH but not in simple steatosis, whereas levels ...
Cell Mol Gastroenterol Hepatol. 2020;10(4):868-880 e861. Article PubMed PubMed Central Google Scholar Lim SO, Li CW, Xia W, Cha JH, Chan LC, Wu Y, Chang SS, Lin WC, Hsu JM, Hsu YH, et al. Deubiquitination and stabilization of PD-L1 by CSN5. Cancer Cell. 2016;30(6):925...
Impact of T-cell therapy on cancer cells. Note:ASchematic diagram of T cell therapy in GC mice;BFlow cytometry for GFP+and mCherry + GC cells;CFlow cytometry results, where CD45- represents non-immune cells, which here refers to cancer cells;DImmunofluorescence results images of tumor ...
The PanMeso cells were cultured in the mesothelial cell media (medium 199 (Gibco/Thermo), 10% FBS, 1% penicillin/streptomycin (Gibco/Thermo), 3.3 nM mouse epidermal growth factor (Biolegend), 400 nM hydrocortisone (MilliporeSigma), 870 nM zinc-free bovine insulin (MilliporeSigma), 20 mM ...
Cell Mol. Immunol. 17, 753–764 (2020). Article CAS PubMed Google Scholar Castro, B. A. et al. Macrophage migration inhibitory factor downregulation: a novel mechanism of resistance to anti-angiogenic therapy. Oncogene 36, 3749–3759 (2017). Article CAS PubMed PubMed Central Google ...
Nonalcoholic steatohepatitis (NASH) is a complex metabolic disease of heterogeneous and multifactorial pathogenesis that may benefit from coordinated multitargeted interventions. Endogenous metabolic modulators (EMMs) encompass a broad set of molecular f