CellularTransportNotes Ch.7.3 AboutCellMembranes 1.Allcellshaveacellmembrane2.Functions:a.Controlswhatentersandexitsthecelltomaintainaninternalbalancecalledhomeostasisb.Providesprotectionandsupportforthecell TEMpictureofarealcellmembrane.AboutCellMembranes(continued)3.Structureofcellmembrane LipidBilayer-2layersof...
There are a variety of proteins in exosomes that affect their sorting and signal transduction processes [22]. Whatever the origin of the exosome, almost all exosomes include proteins involved in membrane transport and fusion (such as RAB GTPases, annexins, and flotillin), proteins that create m...
Lipid bilayer membranes are a central part of cellular architecture and both their molecular organization and total area are tightly regulated by processes such as endocytosis and exocytosis, clathrin coated pits and caveolae, but also mechanical interaction with the underlying cytoskeleton1,2,3,4. Fur...
Cell migration during the invasion-metastasis cascade requires cancer cells to navigate a spatially complex microenvironment that presents directional choices to migrating cells. Here, we investigate cellular energetics during migration decision-making i
Cytosolic transport is an essential requirement but a major obstacle to efficient delivery of therapeutic peptides, proteins and nucleic acids. Current understanding of cytosolic delivery mechanisms remains limited due to a significant number of conflict
Chapter 9—Protein Detection and Analysis Chapter 10—Enzyme Substrates and Assays Chapter 11—Probes for Cytoskeletal Proteins Chapter 12—Probes for Organelles Chapter 13—Probes for Lipids and Membranes Chapter 14—Fluorescent Trace...
Pathway 3: HCC can increase sphingomyelin and cardiolipin production by activating mTORC2. Large amounts of sphingomyelin and cardiolipin are used to assemble cell membranes, which also meet the needs of rapid tumor proliferation. Pathway 4: The accumulation of BCAA can promote the occurrence ...
and chemical composition. If a membrane has holes in its structure, the size and density of those pores determine how well that membrane functions (porosity). For some porous membranes, however, the amount of phase separation between the hydrophobic and hydrophilic membrane phases-referred to as ...
Advanced Membranes and Porous Materials Center, Physical Sciences and Engineering Division, King Abdullah University of Science and Technology, Thuwal, Saudi Arabia Cailing Chen & Yu Han Applied Physics Laboratory, Johns Hopkins University, Laurel, MD, USA ...
transport at the single-cell level47. By using a microfabricated microelectrode chip, the contact of a single cell with the microelectrode was in situ monitored with a microscope, and the single cell-based stepwise short-circuit current output from the microelectrode was simultaneously detected by ...