Diagnosis of non‐follicular Lymphoma (ICD‐10 C83) was confirmed in 2,178 patients, DLBCL (ICD‐10 C83.3) in 819 patients. The analysis was age‐ and gender‐adjusted, observational period was 2014 and 2015. Treatments were analyzed for hospitalization and medication based on ATC code, ...
【疾病名】淋巴瘤细胞白血病 【英文名】lymphoma cell leukemia 【缩写】 【别名】lympho sarcoma cell leukemia 淋巴肉瘤细胞白血病 【ICD 号】C94.7 【概述】 淋巴瘤细胞白血病(lymphoma cell leu-kemia LCL)又称淋巴肉瘤细胞白血病(lympho sarcoma cell leukemia LSL) 由于新的组织学和免疫学研究的进展 LSL 这一名...
IL-7必须与IL-7R结合才能发挥生物效应，主要包括激活JAK/STAT和 PI3K/AKT信号通路，上调抑制细胞凋亡基因BCL-2（B cell lymphoma-2）和下调基因CBL-B（Casitas B-lineage lymphoma B）的表达。
is to provide additional immune stimuli in the form of adjuvants. The combination of local radiotherapy andintratumoral injectionof TLR-9agoniststo the same site induced tumor-reactive memory CD8+T cells and objective clinical responses in a subset of lymphoma patients (Brody et al., 2010). Inte...
【疾病名】淋巴瘤细胞白血病【英文名】lymphomacellleukemia【缩写】【别名】lymphosarcomacellleukemia;淋巴肉瘤细胞白血病【ICD号】C94.7【概述】淋巴..
For angioimmunoblastic T cell lymphoma (AITL), a rare cancer, no specific treatments are available and survival outcome is poor. We previously developed a murine model for AITL that mimics closely human disease and allows to evaluate new treatments. As in human AITL, the murine CD4+ follicular...
The BAX protein, produced by this gene, is a pro-apoptotic factor that promotes cell death by forming homodimers, initiating apoptosis, and inhibiting the anti-apoptotic functions of the B-cell lymphoma-2 gene (Bcl-2). The balance between BAX and Bcl-2 is a crucial factor in regulating ...
T-cell lymphoblastic lymphoma; TM, transmembrane; TNFR, tumor necrosis factor receptor Received 16.10.13; revised 17.1.14; accepted 04.2.14; Edited by T Brunner Fas system deregulation in T-LBL M Villa-Morales et al 2 not only mediated by the FAS system, but it may participate in clonal ...
In patients with hematologic malignancies, including cases of chronic lymphocytic leukemia (CLL) and lymphoma, we observed a reduced antibody response, lower antibody titers, and a compromised humoral immune response following vaccination. Moreover, the treatment's condition is a key factor affecting ...
Mammalian cells responding to specific perturbations of homeostasis can undergo a regulated variant of cell death that elicits adaptive immune responses. As immunogenic cell death (ICD) can only occur in a precise cellular and organismal context, it shou