used mesenchymal stem cells (MSCs) to treat COVID-19 and ARDS. Findings from the analyzed articles indicate a positive impact of stem cell therapy on crucial immunological and inflammatory processes that lead to lung injury in COVID-19 and ARDS patients. Additionally, among the studies, there w...
The significant impact on cell culture development had introduction of the aseptic techniques and Rous and Jones tissue trypsinization technique [70–72]. Rous and his colleague found that use of trypsin solution results in obtaining single cell suspension and cells detachment for subculture. The 3%...
With this encoding scheme, each gene can amplify or diminish its impact on all its neighboring genes according to the corresponding differential expression levels. We discussed the impact of incorporating differential gene expression information on GRN construction using various benchmark datasets, and ...
BergemannC,ReblH,OttoA,MatschkeS,NebeB.Pyruvate as a cell-protective agent during cold atmospheric plasma treatment in vitro: Impact on basic research for selective killing of tumor cells.Plasma Process Polym.2019;16:1900088. AlexandrouC,Al-AqbiSS,HigginsJA,BoyleW,KarmokarA,AndreadiC,etal.Sensiti...
Additionally, the osmoprotective transcription factor TonEBP/OREBP could potentially translocate from the cytoplasm to the nucleus, where it enhanced the transcription of the genes that generated inert osmolytes (sorbitol, betaine, inositol, and taurine) in response to hypertonicity [20]. We also ...
Exportin 1 (XPO1), also known as chromosome region 1 (CRM1), is a regulatory factor necessary for exporting cargo proteins that have the nuclear export signal (NES) from the nucleus to the cytoplasm [6, 7]. CRM1 regulates the nuclear export of more than 200 tumor suppressor proteins and...
Head and neck squamous cell carcinoma (HNSCC) is a very aggressive disease characterized by a heterogeneous tumor immune microenvironment (TIME). Tumor-associated macrophages (TAMs) constitute the major innate immune population in the TIME where they fac
影响因子(Impact Factor,IF)是科睿唯安(Clarivate Analytics)出品的期刊引证报告(Journal Citation Reports,JCR)中的一项数据,对科研人员重中之重的数据。影响因子的计算是某期刊N-1, N-2这两年发表的论文在N年的平均引用次数。以2019年为例,将在2019年6月出的新的影响因子叫“2018年度影响因子”,是2016年和201...
We benchmarked the impact of self-training on the cell type annotation performance by combining the manually annotated dataset with a varying percentage of the most confidently labeled cells. We then used these datasets to train all the cell type annotation methods previously implemented (Fig. 1B)...
Pro-necrotic molecules impact local immunosurveillance in human breast cancer. Oncoimmunology 6, e1299302 (2017). Article PubMed PubMed Central Google Scholar Broz, P., Pelegrin, P. & Shao, F. The gasdermins, a protein family executing cell death and inflammation. Nat. Rev. Immunol. 20, ...