plasma cell (redirected fromPlasma cells) Thesaurus Medical Encyclopedia Related to Plasma cells:Macrophages,Histiocytes,Memory cells n. Any of various short-lived cells that develop from activated B cells and secrete large numbers of antibodies. They are found chiefly in the bone marrow, spleen, ...
Cell-free RNA (cfRNA) in plasma reflects phenotypic alterations of both localized sites of cancer and the systemic host response. Here we report that cfRNA sequencing enables the discovery of messenger RNA (mRNA) biomarkers in plasma with the tissue of origin-specific to cancer types and pre...
Circulating free DNA in plasma or serum as biomarker of carcinogenesis: practical aspects and biological significance. Mutat. Res. 635, 105–117 (2007). CAS PubMed Google Scholar Mouliere, F. et al. Enhanced detection of circulating tumor DNA by fragment size analysis. Sci. Transl Med. 10...
plasma cells areCD19+andCD20−. Abnormal plasma cells are CD19−and CD20−. These cells are typically also CD56+. Up to 20% of cases of neoplasticplasma cell neoplasmsareCD117+. If neoplastic plasma cells are negative for CD56, CD27, or CD45, it is thought to impart a worse ...
Atherosclerosis (AS) is the leading cause of cardiovascular diseases (CVDs) with a high rate of mortality worldwide. Plasma cell-free DNA (cfDNA), mainly originating from apoptosis, necrosis, and active secretion, has been recognized as a promising biomarker for the diagnosis and prognosis of mul...
Figure 1. A: Comparison of four cell-free DNA (cfDNA) isolation methods with the amount of total cfDNA in copies/μL generated with the QIAamp circulating nucleic acid kit (QIA), PME free-circulating DNA Extraction Kit (PME), Maxwell RSC ccfDNA Plasma Kit (RSC), the EpiQuick Circulating...
A bstract : Recent evidence suggests that cell-free plasma DNA has potential use as a prognostic marker in many clinical settings. The aim of the present study was to evaluate the prognostic role of cell-free plasma DNA in the prediction of clinical outcome in intensive treatment unit (ITU)...
对具有mCRPC患者的血浆游离DNA(plasma cell-free DNA)中的72个前列腺癌驱动基因进行了靶向测序,发现34/290(12%)的患者中有37个体细胞突变定位于FOXA1 3'UTR。实际上,FOXA1在所有72个感兴趣的基因中都具有最高的3'UTR突变率,而插入缺失是主要的突变类型。这些插入缺失可以在前列腺肿瘤的早期发现,并且在...
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Plasmacytomas are composed of masses of plasma cells in varying stages of differentiation ▸ Tumor cells may have typical plasma cell morphology with eccentric nuclei and perinuclear hofs, or they may be quite atypical with multinucleated cells ...