细胞死亡与疾病(Cell Death & Disease)是一本由Springer Nature出版的一本CELL BIOLOGY学术刊物,主要报道CELL BIOLOGY相关领域研究成果与实践。本刊已入选来源期刊,属于国际一流期刊。该刊创刊于2010年,出版周期1 issue/year。2021-2022年最新版WOS分区等级:Q1,2023年发布的影响因子为8.1,CiteScore指数15.1,SJR指数2.44...
Cell Death & Differentiation volume 29, pages 1955–1969 (2022)Cite this article 15k Accesses 10 Citations 40 Altmetric Metrics details Abstract Medulloblastoma is the most common malignant brain tumour in children. Genomic studies have identified distinct disease subgroups: wnt/wingless (WNT), sonic...
Laura Brandolini Michele d’Angelo Marcello Allegretti Cell Death & Disease(2022) Cell Death & Differentiation (Cell Death Differ)ISSN1476-5403(online)ISSN1350-9047(print)
Programmed cell deathis any process by which cells participate in their own death. Cell suicide programs are facilitated by the actions of gene products encoded by the cell destined to die. Insufficient or excessive cell death characterizes most human disease states, including virus infections. Pertur...
Many types of human cells self-destruct to maintain biological homeostasis and defend the body against pathogenic substances. This process, called regulated cell death (RCD), is important for various biological activities, including the clearance of aber
In addition, the use of nanotechnology to improve the specificity of autophagy modulators helps to reduce the impact of autophagy therapy on normal cells and achieve the desired antitumor effect. 6. Other forms of non-apoptotic cell death Apart from the aforementioned ferroptosis, necroptosis, ...
[7]. Metastasis is clinically the main cause of death in patients with SCLC. Given the aggressive signature of SCLC, diagnosis should be performed as early as possible. In addition to the usual imaging to define the extent of disease and blood tests, the development of circulating tumor cells...
Recently, the single-cell transcriptome makes possible the in-depth investigation in transcriptional heterogeneity and regulatory mechanism among cell subsets in the developing kidney, providing novel insights into the pathophysiological mechanism for acquired renal disease progression [3,4,5]. These studies...
Cell death in chronic inflammation: breaking the cycle to treat rheumatic disease. Nat. Rev. Rheumatol. 16, 496–513 (2020). Article PubMed Google Scholar Crow, Y. J. & Manel, N. Aicardi–Goutières syndrome and the type I interferonopathies. Nat. Rev. Immunol. 15, 429–440 (2015)...
Cell Death & Disease (2024) Activation of FXR and inhibition of EZH2 synergistically inhibit colorectal cancer through cooperatively accelerating FXR nuclear location and upregulating CDX2 expression Junhui Yu Kui Yang Wei Zhao Cell Death & Disease (2022) Targeting Farnesoid X receptor (FXR) for ...