Cell Cycle and Cell Division - Important notes for NEET Biology. Get access to the complete set of notes for free. Highlighted points to readily grasp and glance through the important notes.
Transferring annotations of single-cell-, spatial- and multi-omics data is often challenging owing both to technical limitations, such as low spatial resolution or high dropout fraction, and to biological variations, such as continuous spectra of cell st
Automatic cell type annotation methods are increasingly used in single-cell RNA sequencing (scRNA-seq) analysis due to their fast and precise advantages. However, current methods often fail to account for the imbalance of scRNA-seq datasets and ignore in
Then, lymphocytes are transported to the tumor site to exert an immune response [16, 17, 19, 20, 22, 56,57,58,59], and an internal cancer-immunity cycle may be formed in these tissues. However, the initiation and process of its formation is still unclear. We found by transcriptome ...
(TSNE). In addition, we used the CellCycleScoring function of the R package Seurat (version 4.0.0) [25] to infer the cell cycle phase of each subset. Moreover, we constructed a clustering tree based on the similarity of cell subsets with the BuildClusterTree function of the R package ...
We then characterized the function of genes that showing different R-loop peaks after A3B knockdown. The R-loop peaks of a total of 459 genes were depleted by A3B knockdown, most of which function in stress response and cell cycle processes (Fig.3E). From this observation, we reasoned tha...
Cycle - Groups of channels (usually 3 or 4) captured between dye exchange cycles Region - Groups of tiles often collected as square grids This seven dimensional structure, illustrated in Fig. 1, is common in multiplexed imaging but dimensions of length 1 are also supported in nearly all ca...
(p-value > 0.05; Figure5C). MDM2 is a target gene of the transcription factor tumor protein p53 and also affects the cell cycle, apoptosis, and tumorgenesis through interactions with other proteins. Over expression of this gene results in excessive inactivation of tumor protein p53, ...
R. et al. A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell 185, 654–671.e22 (2022). Article CAS PubMed PubMed Central Google Scholar Kim, D.-W. et al. Multimodal analysis of cell types in a hypothalamic node controlling social ...
cycle phases and order them on a continuous path analogous to cell-cycle pseudotime (Fig.1d, Methods and Supplementary Notes3,4). To automatically classify cells according to cell-cycle stage, CellCycleTRACER exploits a new machine learning approach that combines decision trees and Gaussian mixture...