View chapter Explore book Tumor Immunology and Immunotherapy – Cellular Methods Part B GiuliaCerrato, ...GuidoKroemer, inMethods in Enzymology, 2020 7Bone marrow-derived dendritic cells (BMDC) culture 1. BMDC are isolated postmortem from C57BL/6 using a sterile scalpel. Femur and thetibiaare ...
A Historical Notes Malignancies of the hematopoietic system were first recognized clinically in the mid-1800s. The German physician Rudolf Virchow observed greatly increased numbers of white blood cells in the blood smear of one of his patients, and coined the term leukemia (meaning “white blood”...
Chapter © 2021 Development of a 48-Well Dynamic Suspension Culture System for Pancreatic Differentiation from Human Embryonic Stem Cells Article 02 December 2021 Background Human-induced pluripotent stem cells (iPSCs) possess the potential to revolutionize the field of regenerative medicine, offeri...
Chapter © 2022 Tumor intrinsic immunity related proteins may be novel tumor suppressors in some types of cancer Article Open access 29 July 2019 CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity Article Open access...
2.1.939 Part 3 Section 19.843, text:note-class 2.1.940 Part 3 Section 19.845, text:number-lines 2.1.941 Part 3 Section 19.846, text:number-position 2.1.942 Part 3 Section 19.850, text:outline-level 2.1.943 Part 3 Section 19.850.5, text:index-entry-chapter 2.1.944 Part 3 Secti...
K. et al. Chapter 11—reconstitution of membrane proteins in phospholipid bilayer nanodiscs. Methods Enzymol. 464, 211–231 (2009). Article CAS PubMed PubMed Central Google Scholar Bayburt, T. H. & Sligar, S. G. Membrane protein assembly into Nanodiscs. FEBS Lett. 584, 1721–1727 (...
Chapter Google Scholar Winding P, Berchtold MW. The chicken B cell line DT40: a novel tool for gene disruption experiments. J Immunol Methods. 2001;249:1–16. Article CAS PubMed Google Scholar Shinohara H, Yasuda T, Aiba Y, Sanjo H, Hamadate M, Watarai H, et al. PKCβ regulates...
Chapter Google Scholar Isensee F, Jaeger PF, Kohl SAA, Petersen J, Maier-Hein KH. nnU-Net: a self-configuring method for deep learning-based biomedical image segmentation. Nat Methods. 2021;18:203–11. Article CAS Google Scholar He K, Gkioxari G, Dollár P, Girshick R. Mask R-CNN....
Review ReportsVersions Notes Simple Summary Cancer treatments have significantly changed with the introduction of immunotherapy. Recently, the development of new agents that harness the redirection of T-cells against cancer is rapidly emerging in multiple tumor types. Since bispecific T-cell engager (BiTE...
αβ T cells express CD4 or CD8 coreceptor molecules that bind to a non-polymorphic region of MHC class II or I, respectively, to increase T cell-APC adhesion and facilitate T cell activation. View chapterExplore book T CELLS AND THE THYMUS In Immunology Guidebook, 2004 T cell receptor ...