doi:10.1002/yea.1864John Wiley & Sons, Ltd.Yeast
A conserved mitotic kinase active at late anaphase|[mdash]|telophase in syncytial Drosophila embryos MUTATIONS in the Drosophila gene polo cause abnormal mitotic and meiotic divisions 1,2 . This gene encodes a 577-amino-acid protein that has an N-termina... B Fenton,DM Glover - 《Nature》 ...
Dancing the cell cycle two-step: regulation of yeast G1-cell-cycle genes by chromatin structure. Trends Biochem Sci. 2013;38:467–75. Article CAS PubMed PubMed Central Google Scholar Barnaba N, LaRocque JR. Targeting cell cycle regulation via the G2-M checkpoint for synthetic lethality ...
Each trace represents the Venus intensity as a function of time in a single yeast cell over multiple cell cycles. The vertical dash lines indicate the cell division time. In most cells, KIP1pr, but not PRX1pr, shows strong cell cycle-regulated activity. (c) Selected traces of PRX1pr-...
The serine/threonine kinase PLK family's prominent member, Polo-like kinase 1 (PLK1), has been extensively studied for its critical role in cell cycle progression, encompassing the fundamental aspects of chromosome segregation, centrosome maturation, and cytokinesis. However, the function of PLK1 ...
C. Protein arms in the kinetochore–microtubule interface of the yeast DASH complex. Mol. Biol. Cell 18, 2503–2510 (2007). Article CAS PubMed PubMed Central Google Scholar Wang, H. W. et al. Architecture of the Dam1 kinetochore ring complex and implications for microtubule-driven ...
Further, the cells show bud-scaring typical of the species’ reproduction cycle (green arrow in Fig. 2A). TEM images of ultrathin sections ∼ 90 nm of untreated C. albicans were obtained that provided an insight of the cellular ultrastructure (Fig. 2B). In this process, the samples were...
Jayadev, S., Liu, B., Bielawska, A. E., Lee, J. Y., Nazaire, F., Pushkareva, M. Y., et al. (1995) Role for ceramide in cell cycle arrest.J. Biol. Chem.270, 2047–2052. PubMedCASGoogle Scholar Jarvis, W. D., Kolesnick, R. N., Fornari, F. A., Traylon, R. S...
Only a small part of glucose-derived carbon enters the tricarboxylic acid (TCA) cycle. The cell culture medium is acidified by the lactate secretion and is not adequate for cell survival and production of NDV. To overcome this problem, the expression level of lactate dehydrogenase (LDH), ...
Cell cycle G2 arrest induced by HIV-1 Vpr is thought to benefit viral proliferation by providing an optimized cellular environment for viral replication and by skipping host immune responses. Even though Vpr-induced G2 arrest has been studied extensively