Cell-to-cell interactionis one of the most important cellular functions in an organism, the disruption of which certainly has known and still unknown consequences. It is questionable whether the few cells from whichimmortalized cell linesoriginate, are representative of their tissue or disease of ori...
The pipeline integrates the RNA-seq and PPI datasets by using the analysis setups. It generates an interaction space containing an instance for each sample/cell type, containing the values assigned to each protein in the PPI list given the setups for computing the CCI and CCC scores. interact...
Cell-Cell Interaction Database : https://baderlab.org/CellCellInteractions#ref6 Cell-Cell Interaction Database 描述了通过过滤已有的蛋白质-蛋白质相互作用(PPI)数据,细胞-细胞相互作用数据库的自动构建。细胞间的相互作用对理解组织结构很重要。我们和其他人建立了细胞-细胞相互作用数据库(1,2,3,4,5)。这个...
cell-cell interaction (CCI)(细胞间相互作用) spatial transcriptomics(空间转录组学) DeepCOLOR(DeepCOLOR) 研究背景 单细胞转录组分析技术揭示了细胞异质性,对理解疾病发展至关重要。 细胞状态的转变及其调控机制需要考虑细胞间相互作用的影响。 空间转录组学技术提供了细胞空间分布的分子信息,但存在分辨率限制或预设基...
SPACE 使用图自编码器 (Graph autoencoder) 框架来学习低维的细胞嵌入,该细胞嵌入描述了空间转录组数据中每个细胞自身的基因表达信息以及其与空间邻近细胞的相互作用信息(因此称该细胞嵌入为细胞-细胞相互作用感知的细胞嵌入,cell-cell interaction-aware cell embedding)。在该细胞嵌入基础上,SPACE 再通过聚类算法识别空...
破骨细胞( Osteoclasts) 细胞间交互作用( Cell-cell interaction) 骨基质( Bone matrix) ... www.op90.com|基于15个网页 2. 细胞间互动 ...变而成,细胞的复制(proliferation)及细胞间互动(cell-cell interaction) 的控制都变的不正常,现今己知有两大类基因参与其中: …wwwu.tsgh.ndmctsgh.edu.tw|基于2...
SPACE 使用图自编码器 (Graph autoencoder) 框架来学习低维的细胞嵌入,该细胞嵌入描述了空间转录组数据中每个细胞自身的基因表达信息以及其与空间邻近细胞的相互作用信息(因此称该细胞嵌入为细胞-细胞相互作用感知的细胞嵌入,cell-cell interaction-aware cell embedding)。在该细胞嵌入基础上,SPACE 再通过聚类算法识别空...
HyperAI超神经此前曾解读分享了李雨哲博士为第一作者的研究论文「Tissue module discovery in single-cell resolution spatial transcriptomics data via cell-cell interaction-aware cell embedding」。 研究亮点 * 开发了空间转录组数据人工智能分析工具 SPACE,可从单细胞分辨率的空间转录组数据中,识别空间细胞类型并发现...
Aberrant epithelial cell interaction via EFNB1-EPHB4 plays a role in mouse ESCC formation By Visium spatial transcriptomic sequencing, we analyzed five distinct tissues, i.e., normal (NOR), INF, LGIN, HGIN and ESCC, taken at different time from a mouse model treated with chemical carcinogen ...
Cell Interactiondoi:10.1007/978-1-4020-6754-9_2625The influence of cells on each other during differentiation and development. contact inhibition, nurse cells, morphogenesis, maternal effect genesSpringer NetherlandsEncyclopedia of Genetics Genomics Proteomics & Informatics...