The IgG Purity and Heterogeneity Assay provides high-resolution separation for either reduced or non-reduced IgG molecules. 关于CE-SDS 毛细管凝胶电泳应用的更多信息,请参见下面的应用通讯: “Assay of IgG Purity and Heterogeneity Using High-Redolution Sodium Dodecyl Sulfate Capillary Gel Electrophoresis” ...
[1]. Gel US Patent # US7,381,317. Automating the process of gel replacement is disclosed in US. [2]. Patent # USRE37,606. [3]. Chemistries referenced in USP Chapter<129>. [4]. A Series of Collaborations between Various Pharmaceutical Companies and Regulatory Authorities Concerning the An...
Reduced CE-SDSLight chain dimerCapillary temperatureCapillary electrophoresis sodium dodecyl sulfate (CE-SDS), either in reduced (rCE-SDS) or non-reduced (nrCE-SDS) form, is widely used for purity evaluation and impurity analysis of monoclonal antibody (mAb) drugs. The accuracy of the method may...
Capillaries of the1D CE(SDS) separation were conditioned prior to each measurement by flushing with 0.1 M NaOH, 0.1 M HCl and water at 3 bar for 3 min. For the injection via valve experiments (no separation in the1D), the capillaries of the1D were flushed with reduced NIST ...