Decreased Cdc42 expression is also observed in podocytes of patients with diabetic DN or FSGS. Moreover, we found that podocyte apoptosis was increased in Cdc42 deficiency podocytes in vivo and in vitro. We also further demonstrated that the loss of Cdc42 or its downstream effector Nwasp-...
Diabetes could cause many complications including diabetic nephropathy (DN), diabetic retinopathy and diabetic foot. Furthermore, hyperglycemia can promote tumor progression and increase the risk of malignant cancers. In this review, we summarized the regulation of Cdc42 in insulin secretion and diabetes...
Practical guidelines on the management and prevention of the diabetic foot: based upon the International Consensus on the Diabetic Foot (2007) Prepared by the International Working Group on the Diabetic Foot[J]. Diabetes Metab Res Rev, 2008, 24 Suppl 1:S181-187. [11] American Academy of ...
- 《Diabetes Care》 被引量: 73发表: 2011年 Diabetic foot disorders. A clinical practice guideline. For the American College of Foot and Ankle Surgeons and the American College of Foot and Ankle Orth... Foot ulcerations, infections, and Charcot neuropathic osteoarthropathy are three serious ...