Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33. Article PubMed Google Scholar Villani A, Potestio L, Fabbrocini G, Troncone G, Malapelle U, Scalvenzi M. The treatment of Advanced Melanoma: therapeutic update. Int J Mol Sci 2022, 23(12). Ribas A, Wolchok JD. Cancer...
Colon adenocarcinoma (COAD) is the second leading cause of cancer death, and there is still a lack of diagnostic biomarkers and therapeutic targets. In this study, bioinformatics analysis of the TCGA database was used to obtain RUNX1, a gene with prognostic value in COAD. RUNX1 plays an imp...
High-grade glioma is the most common and aggressive primary brain tumor in adults with poor therapeutic efficiency and survival prognosis. Cell division cycle associated 8 (CDCA8) has been well known as a cell cycle regulator and tumor promotor in variou
[1]SUNG H, FERLAY J, SIEGEL R L, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries [J]. CA Cancer J Clin, 2021, 71(3): 209-49. [2]WHITE S R, LAURING B. AAA+ ATPases: achieving diversity of function ...
Farid B. Ahmad, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues examined mortality in the United States using provisional data, based on preliminary death certificate data, for 2023. The researchers found a provisional total of 3,090,582 deaths ...
本研究旨在通过癌症基因组图谱(The Cancer Genome Atlas,TCGA)、高通量基因表达(Gene Expression Omnibus,GEO)数据库,应用生物信息学方法分析CDC20在肺腺癌中的表达及其与生存预后的相关性。通过基因集富集分析(gene set enrichment analy...
方法:利用癌症基因组图谱(The Cancer Genome Atlas,TCGA)和基因表达谱数据动态分析(Gene Expression Profiling Intera-ctive Analysis,GEPIA)数据库分析胰腺癌组织及癌旁组织中CDCA7表达水平的差异,并采用实时荧光定量PCR和蛋白质印迹法分别检测...
Triple-negative breast cancer (TNBC),Cell division cycle 20 (Cdc20),Proliferation,Metastasis,Mitotic inhibitorsThese results suggest an essential role of Cdc20 in tumor formation and metastasis of TNBC, which might be a potential target therapy for TNBC treatment....
Statistics and reproducibility The data are presented as the means ± S.E.M. Unpaired, two-tailed Student’sttest or one-way analysis of variance with Dunnett multiple comparisons test was performed as indicated to determine significant differences. All statistical analyses were performed using GraphPa...
(also called inflamed or hot tumors) across multiple cancer types20,21,22,23. However, a large proportion of cancers as non-inflamed tumors (also called cold tumors) are still refractory or poorly responsive to ICIs24. Combination therapies are a promising strategy to clinically improve ICI ...