Colon adenocarcinoma (COAD) is the second leading cause of cancer death, and there is still a lack of diagnostic biomarkers and therapeutic targets. In this study, bioinformatics analysis of the TCGA database was used to obtain RUNX1, a gene with prognostic value in COAD. RUNX1 plays an imp...
Farid B. Ahmad, M.P.H., from the National Center for Health Statistics in Hyattsville, Maryland, and colleagues examined mortality in the United States using provisional data, based on preliminary death certificate data, for 2023. The researchers found a provisional total of 3,090,582 deaths i...
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2024, 74, 229–263. [Google Scholar] [CrossRef] Larsen, B.D.; Benada, J.; Yung, P.Y.K.; Bell, R.A.V.; Pappas, G.; Urban, V.; Ahlskog,...
[1] Agostinetto E, et al. Emerging treatments in HER2-positive advanced breast cancer: Keep raising the bar. Cell Rep Med. 2024;5(6):101575. [2] Giaquinto AN, et al. Breast Cancer Statistics, 2022. CA Cancer J Clin. 2022;72(6):524-541. [3] Swain SM, ...
(+ +), and 9–12 as (+ + +). Finally, we set “+“ as WTX expression cut off point: − as negative;+ ~ + + + as positive4. The clinical pathologic meanings of the IHC data were analyzed by Chi-square analysis. IHC staining and statistics were performed in a...
The pseudokinase NRBP1 activates Rac1/Cdc42 via P-Rex1 to drive oncogenic signalling in triple-negative breast cancer. Oncogene 2023, 42, 833–847. [Google Scholar] [CrossRef] [PubMed] Murphy, N.P.; Binti Ahmad Mokhtar, A.M.; Mott, H.R.; Owen, D. Molecular subversion of Cdc42 ...
2023年CSCO骨与软组织肿瘤指南相较于此前版本,新增骨盆骨肉瘤的外科治疗分层选择(详见下表)。 表1 骨盆骨肉瘤的外科治疗策略 2、术中操作实施 目前,单纯的影像学导航技术在指导软组织肿瘤手术中的应用受限,因为它无法适应术中位置变化,进而影响手术的精度、安全性或...
Cancer statistics, 2021. CA Cancer J Clin. 2021;71(1):7–33. Article PubMed Google Scholar Villani A, Potestio L, Fabbrocini G, Troncone G, Malapelle U, Scalvenzi M. The treatment of Advanced Melanoma: therapeutic update. Int J Mol Sci 2022, 23(12). Ribas A, Wolchok JD. Cancer...
Grisly though these statistics are, they are still tiny when set beside the number of lives lost to breast cancer (41,000 each year) and lung cancer (1,000). Advocates for more money for child cancer prefer to look at life-years lost. The average age for cancer diagnosis in a young ...
CDK4/6 inhibition triggers ICAM1-driven immune response and sensitizes LKB1 mutant lung cancer to immunotherapy. Nat. Commun. 14, 1247 (2023). Article ADS CAS PubMed PubMed Central Google Scholar Patterson-Fortin, J. et al. Polymerase theta inhibition activates the cGAS-STING pathway and ...