AIH患者肝内IL-15和TGF-β表达水平显著升高,且肝细胞广泛表达CD103配体- E-钙黏蛋白(E-cadherin),这些因素可能有助于CD8+ TRM细胞的分化和驻留。经过免疫治疗后,AIH患者肝内CD8+ TRM细胞数量显著下降。糖皮质激素可以通过直接下调CD8+ TRM细胞Blimp1的表达,从而抑制CD8+ TRM细胞的体外扩增。 该研究证实了CD69+...
and the functioning transcription factors were predicted using the UCSC and JASPAR databases.We found that different CD8 + TRM subsets existed in CRC tumor tissues, which were identified as CD69 CD103 CD8 + TRM, CD69 + CD103 CD8 + TRM (SP CD8 + TRM), and CD69 + CD103 + CD8 + TRM...
3.4.1CD69 and CD103 According to recent studies,CD69is considered to play a key function in retaining TRM cells in tissues whereas CD103 expressed by TRM cells interact with E-cadherin on the epithelial cells in order to promote resident phenotype in TRMT cells[28,73,74]. Recent studies ...
车牌号码闽CD10369五行分析 闽CD10369 五行数理:49分 五行属性:金属性 五行阴阳:阳 吉凶分析:遇吉则吉,遇凶则凶,惟靠谨慎,逢凶化吉(凶) 主人个性:主人性格类型:[大胆行事冲动派型],其具体表现为:爱好追寻刺激,有不理后果大胆行事的倾向。崇尚自由奔放的恋爱,会拼尽全力爱一场,是就算明知无结果都在所不惜的...
et al. The developmental pathway for CD103+CD8+ tissue-resident memory T cells of skin. Nat. Immunol. 14, 1294–1301 (2013). Article CAS PubMed Google Scholar Awasthi, A. et al. Cutting edge: IL-23 receptor gfp reporter mice reveal distinct populations of IL-17-producing cells. J. ...
et al. Intestinal CD103 þ , but not CX3CR1 þ , antigen sampling cells migrate in lymph and serve classical dendritic cell functions. J. Exp. Med. 206, 3101–3114 (2009). This work is licensed under the Creative Commons Attribution-NonCommercial-No Derivative Works 3.0 Unported ...
Immunologists' views on the cellular basis of immune memory have undergone substantial modifications over the last decade, with new findings advancing the field from mostly descriptive studies of their presumptive phenotypes to those that allow the features distinguishing memory cells from short-lived effe...
研究者通过对比慢性乙型肝炎、非酒精性脂肪性肝病和健康人的组织,发现AIH患者肝内CD69+ CD103+ CD8+ TRM 细胞显著增加,且与疾病严重程度呈正相关。 该研究证实了CD69+ CD10…
摘要: 篇首: 强直性脊柱炎(ankylosing spondylitis,AS)是一种主要侵犯脊柱,并累及骶髂关节和周围关节,以慢性进行性炎症为主要表现的自身免疫性疾病.关键词:外周血T细胞亚群 强直性脊柱炎 CD 检测 自身免疫性疾病 粘附分子表达 骶髂关节 流式细胞仪 DOI: 10.3969/j.issn.1006-1703.2007.01.017 被引量: 14 ...
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