Effect of phytohaemag- glutinin on CD45 in T cells. Immunol Letters 1994; 42:197-201.Monostori,E., Hartyani,Z., Ocsovszky,I., Hegedus,Z., Oravecz,T., Kalman,M. and Ando,I. (1994) Effect of phytohaemagglutinin on CD45 in T cells. Immunol. Lett., 42, 197-201....
CD45其胞浆区段具有蛋白质酪氨酸磷酸酶的作用,能使底物P56lck和P59fyn上酪氨酸脱磷酸而激活,在细胞的信息传导中发挥重要作用,CD45是细胞膜上信号传导的关键分子,在淋巴细胞的发育成熟,功能调节及信号传递中具有重要意义,CD45的分布可作为某些T细胞亚群的分类标志。同时CD45分子在所有白细胞上都有...
In the absence of cell-surface cancer-specific antigens, immunotherapies such as chimeric antigen receptor (CAR) T cells, monoclonal antibodies, or bispe
CD62L is a 74-95 kD glycoprotein,also known as L-selectin, LECAM-1, Ly-22 and MEL-14.It is a member of the selectin family and is expressed on the majority of B and naïve T cells,a subset of memory T cells,granulocytes ...
We have studied the alterations in CD45R phenotypes of CD4+CD45RA–RO+ T cells in recipients of T cell-depleted bone marrow grafts. These patients are convenient models because early after transplantation, their T cell compartment is repopulated through expansion of mature T cells and contains on...
产品名称 Human Naive CD4+/CD45RA+ T Cells (Cord Blood) (Lonza, CAT#4C-202) 货号: 4C-202 规格: 品牌: Lonza 价格: ¥请咨询 产品分类: 细胞培养相关产品 研究领域: Primary and Stem Cells CAS编号: 分子量: 分子式: 别名: 储存条件: 运输条件: 货期: 现货 应用: 说明书: 备注: ...
1. CD45RA CD45RA contains exon 4 but lacks exon 5 and 6. It's expressed onnaïve T cells. 2. CD45RO CD45RO contains exon 3, 7 and 8 and lacks the RA, RB and RC exons of the CD45 gene. CD45 isoforms with short extracellular domains homodimerize more easily than those with ...
Figure 1. Regulation of Lck Activity by the Opposing Actions of Kinases and Phosphases The regulatory Tyr (Y505) of Lck is phosphorylated by the kinase Csk, which maintains Lck in an inactive conformation. The dephosphorylation of Y505 by CD45 in resting T cells sustains a pool of basally...
Identify T cell subsets (i.e. memory T cells) 商品化试剂(排名不分先后,本网站对抗体质量不负责!)公司 克隆号 即用型(ml) 原液(ml) 赛诺特 UCHL1 1 3 6 / 0.1 0.2 基因科技 UCHL1 1 2 4 7 / 0.2 中杉金桥 UCHL1 1.5 3 6 / 0.1 0.2 安必平 UCHL-1 1.5 3 6 / 0.1 0.2 福...
参考文献:Larbi, A. and Fulop, T. (2014), From “truly naïve” to “exhausted senescent” T cells: When markers predict functionality. Cytometry, 85: 25-35. https://doi.org/10.1002/cyto.a.22351 本文来自流式中文网(flowcyto...