CD62L(L-选择素)是一种黏附分子,属于选择素家族。它主要表达在白细胞表面,包括T细胞、B细胞和自然杀...
调节性T细胞(regulatory T cells,Treg),是一类具有显著免疫抑制作用的T细胞亚群。Treg作为免疫系统的调...
The rate of CD62L cells did not differ among groups for either PBMCs or WC1.1+ γδ T cells. A higher GMFI of CD62L in prolif-erative PBMCs than nonproliferative PBMCs upon stimulation with S. aureus was detected, whereas no impact on the GMFI of CD62L was observed in WC1.1+ ...
Besides, RES decreased the number of CD4+ T cells in peripheral blood, decreased the expression of CD25 and CD44, but not affected the expression of L-selectin (CD62L). In vitro, RES decreased the expression of Ki67, CD25 and ... L Zhou,J Long,Y Sun,... - BioMed Central 被引量:...
Mouse CD4+T cells develop in the thymus and are released as naïve T cells that also express CD62L and low levels of CD44. These cells differentiate into subsets of specialized effector T lymphocytes in response to distinct environmental cues and the activation of specific transcription facto...
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis. IL-17-producing CD8+ T (Tcl7) cells are detectible in multiple sclerosis (MS) lesions; however, their contri-bution to the disease is unknown. To identify ... Huber,Magdalena - 《Journal of Clinical Investi...
Objective CD44HighCD62L- is the marker for effector memory T cell. It is well-known that CD4+ T memory cells (Tms) play important role in asthma, but the role of CD8+ T memory cells (Tms) in asthma remains unknown. Here, we analyzed the variation of CD4-Tms in asthmatic mice so ...
推荐其采用的方案是CD3、CD4、CD8、CD45RA、CCR7、CD45RO。当然,大家也可以根据自己的喜好选择增加其它标记,例如CD62L、CD95等。 参考资料: T细胞亚群细分标记 T细胞接受抗原刺激后的五个阶段及其表型 T细胞耗竭四阶段 Flynn, J. K. & Gorry, P. R. Stem memory T cells (TSCM)—their role in cancer ...
结论:小鼠脾脏淋巴细胞体外培养后,细胞表面标记物 CD44和CD62L 发生巨大变化,CD62L 呈现明显下调趋势,接近消失,CD44 也有下调。[关键词] 表面标记物;小鼠;淋巴细胞Changes of cell surfa c e markers CD3,CD4,CD44,CD62L on mouse spleen lym-phoc y t e s a f ter cu l tur e in vitroLI Yan-Chun...
【关键词】溃疡性结肠炎;清肠栓;葡聚糖硫酸钠;CD44;CD62L;T淋巴细胞;小鼠 【中图分类号】 R285.5 【文献标志码】 A 【文章编号】 1007—1334(2014)05—0104—05 Efectof“QingchangSuppository”onexpressionofCD44andCD62LinsplenicCD4 T—cellsin micewithcolitisinducedbydextransulfatesodium WANGLi—Juan,LIU...