共鉴定出16个细胞群,包括8个CD4细胞群和8个CD8细胞群。对这些群一一命名和按marker注释,不是重点这里就不展开了。 DP细胞由高IRScore细胞组成,而DN细胞中最少。CD8细胞的IRScore明显高于CD4细胞,因为CD8细胞中DP细胞的百分比更高。DP细胞显示出细胞毒性和耗竭标记基因表达,而DN细胞具有更高的幼稚基因表达,SP细胞则...
共鉴定出16个细胞群,包括8个CD4细胞群和8个CD8细胞群。对这些群一一命名和按marker注释,不是重点这里就不展开了。 DP细胞由高IRScore细胞组成,而DN细胞中最少。CD8细胞的IRScore明显高于CD4细胞,因为CD8细胞中DP细胞的百分比更高。DP细胞显示出细胞毒性和耗竭标记基因表达,而DN细胞具有更高的幼稚基因表达,SP细胞则...
FOXP3+ Treg cells, an immune-suppressive CD4+ T cell subset with high CD39 expression, modulate immune activities through a variety of mechanisms, including the CD39-dependent production of adenosine [61,62,63,64]. CD39 represents a suppressive function marker in Treg cells. According to the...
肺腺癌 ; CD39 ; 免疫微环境 ; 化疗敏感性 ; 免疫治疗 [摘要] 目的 采用生物信息学方法探讨CD39基因在肺腺癌组织中的表达情况,并分析CD39与肺腺癌免疫微环境及免疫治疗响应的关系。方法 通过The Cancer Genome Atlas (TCGA)数据库分析CD39在肺腺癌组织和正常肺组织中的表达差异。采用基因集富集分析(GSEA)研究...
a B lymphocyte cell surface marker (2), but it is also present on the surface of natural killer cells, T cells, and some endothelial cells (3). NTPDase-1 hydrolyzes the beta - and gamma phosphate residues of nucleotides, preferring ATP as the substrate. Through its hydrolysis of extracell...
预染蛋白Marker分子量标准(10-260kDa) 2x250μl/50次MBI原装 ZNF268英文名称:锌指脂蛋白-1b抗体0.2ml DAB2IP英文名称:Dab2相互作用蛋白抗体0.2ml FLT1 VEGFR1 / FLT-1兔单抗Human 乙酰三尖杉碱HPLC≥98% 5mg Raetinolbindingprotein4,RBP-4ELISA试剂盒大鼠视黄醇结合蛋白4(RBP-4)ELISA试剂盒规格:96T/48T ...
Ectonucleoside triphosphate diphosphohydrolase-1 (NTPDase-1) is an integral membrane protein with an extracellular active site. NTPDase-1 was originally described as CD39, a B lymphocyte cell surface marker (1), but it is also present on the surface of natural killer cells, T cells,...
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Identification of CD39 as a Marker for the Circulating Malignant T-Cell Clone of Sézary Syndrome PatientsHD healthy donorSS Sézary syndromeTCR T-cell receptorOpen this preview in PDFClick to open first page previewOpen this preview in PDFdoi:10.1016/j.jid.2018.09.026Bensussan, Armand...
Sepsis Regulatory T cell CD39 Prognosis 1. Introduction Sepsis, defined as a systemic inflammatory response to infection, is associated with high mortality in critically ill patients.1, 2 Patients with sepsis often develop organ dysfunctions, including tissue hypoperfusion and hypoxia, lactic acidosis,...