共鉴定出16个细胞群,包括8个CD4细胞群和8个CD8细胞群。对这些群一一命名和按marker注释,不是重点这里就不展开了。 DP细胞由高IRScore细胞组成,而DN细胞中最少。CD8细胞的IRScore明显高于CD4细胞,因为CD8细胞中DP细胞的百分比更高。DP细胞显示出细胞毒性和耗竭标记基因表达,而DN细胞具有更高的幼稚基因表达,SP细胞则...
Background: Drug-reactive T cells are involved in most drug-induced hypersensitivity reactions. The frequency of such cells in peripheral blood of patients with drug allergy after remission is unclear. Objective: We determined the frequency of drug-reactive T cells in the peripheral blood of ...
On the other hand, it is well established that integrin αE (geneITGAEencoding CD103) pairs with integrin β7 (geneITGB7) on murine and human immune cells. CD103 is considered a key phenotypic marker of resident memory T (TRM) cells in a variety of tissues including tumors. In cancer, ...
In contrast, Foxp3, a marker of regulatory T cells, was expressed in DC aggregates on T-cell transfer, coinciding with the appearance of CD103+ CD25− T cells in these clusters. Foxp3 was enriched in the CD103+ T-cell fraction isolated from the lamina propria of diseased mice. T-...
近期,美国东北大学药学系Mansoor Amiji团队在《Journal of Controlled Release》杂志第345期上发表题为“Systemic nano-delivery of low-dose STING agonist targeted to CD103+dendritic cells for cancer immunotherapy”的研究性论文,报道...
Flow cytometry was performed using a FACSCalibur (BD bioscience), and data were analyzed using FlowJo (TreeStar, Inc., Ashland, OR, USA) software. The percentage of positive cells for a given marker was based on cutoff points chosen to exclude >99% of the negative control population. For ...
CD103 Is a Marker for Alloantigen-Induced Regulatory CD8+ T Cells The alphaEbeta7 integrin CD103 may direct lymphocytes to its ligand E-cadherin. CD103 is expressed on T cells in lung and gut and on allograft-infiltrating... E Uss,AT Rowshani,B Hooibrink,... - 《Journal of Immunology...
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In vitro stimulation of human T cells with mitogens induces upregulation of CD103. Epithelial cell antigen (E-cadherin) binds to CD103 and mediates homing of lymphocytes to the intestinal epithelium. 产品留言 标题 联系人 联系电话 内容 验证码 点击换一张 注:1.可以使用快捷键Alt+S...
Evaluation of CD103 as a cellular marker for the diagnosis of pulmonary sarcoidosis A high CD4+/CD8+ ratio in bronchoalveolar lavage fluid is indicative for the diagnosis pulmonary sarcoidosis but this ratio only does not fully discriminat... Michiel,Heron,and,... - 《Clinical Immunology》 被引...