CD30阳性皮肤T细胞淋巴瘤(CD30 positive cutaneous T cell lymphoma) 又称原发性CD30阳性皮肤T细胞淋巴瘤,为单发性或局限性皮肤损害,倾向溃疡(50%)和自然消退(25%)。罕见于儿童,男性多于女性。 审编医生
CD30阳性皮肤T细胞淋巴瘤(CD30positivecutaneousTcelllymphoma)又称原发性CD30阳性皮肤T细胞淋巴瘤,为单发性或局限性皮肤损害,倾向溃疡(50%)和自然消退(25%)。罕见于儿童,男性多于女性。
Summary. CD30, Ki-1 antigen, an activated T-cell antigen, is a member of the nerve growth factor receptor family. This antigen is expressed on the lymphoma cells of some adult T-cell leukaemia/lymphoma (ATL/L) patients and some patients with Epstein-Barr virus infection. CD30-positive ...
ADC),最早被美国食品药品监督管理局(FDA)批准用于复发难治性霍奇金淋巴瘤(Hodgkin's lymphoma,HL)和系统性间变大细胞淋巴瘤(systemic anaplastic large cell lymphoma ,sALCL)的治疗,2018年11月美国FDA批准BV 联合化疗方案用于初治的CD...
CD30-posi- tive cutaneous T-cell lymphoma and response to brentuximab vedotin: 2 illustrative cases. Clin Lym- phoma Myeloma Leuk 2013;13(3):319-23.Mody K, Wallace JS, Stearns DM et al. CD30-positive cutaneous T- cell lymphoma and response to Brentuximab Vedotin: 2 illustrative cases. ...
陈洁宇:CD30是肿瘤坏死因子受体超家族成员,在经典型霍奇金淋巴瘤(classical Hodgkin lymphoma,CHL)、间变性大细胞淋巴瘤(anaplastic large cell lymphoma,ALCL)等多种淋巴瘤中均有不同程度的表达。除了作为诊断和评价预后的标志物,CD30还...
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CD30-Positive Anaplastic Large Cell Lymphoma Cell Lines. In: JRW Masters, Palsson BO, eds. Human Cell Culture: Cancer Cell Lines, pt 3:Leuke- mias and Lymphomas. Vol 3. Netherlands: Springer; 2000:355-370.Herbst H, Drexler HG. CD30-positive anaplastic large cell lymphoma cell lines. In...
Horwitz S, O'Connor OA, Pro B, et al. Brentuximab Vedotin with chemotherapy for CD30-positive peripheral T-cell lymphoma (ECHELON-2):A global, double-blind, randomised, phase 3 trial[J]. Lancet, 2019, 393(10168):2...
I think the challenge is just CD30-positive peripheral T-cell lymphoma remains a disease that responds quite poorly to chemotherapy, particularly just typical CHOP chemotherapy. In contrast, the patients who have anaplastic large cell lymphoma, which is very positive for CD30, just standard CHOP ...