(2010). “Pharmacology of anti-CD3 diphtheria immunotoxin in CD3 positive T-cell lymphoma trials.” Methods Mol Biol 651: 157-175 Flow cytometry Rossi, N. E., et al. (2008). “Differential antibody binding to the surface alphabetaTCR.CD3 complex of CD4+ and CD8+ T lymphocytes is ...
Diffuse large B-cell lymphomaCD3Aberrant expressionAntigen lossRelapseAberrant expression of CD3 on diffuse large B-cell lymphoma (DLBCL) is rare, and its mechanism and biological significance are currently unclear. Herein we report a case of Epstein-Barr virus-negative, CD3-positive DLBCL in a 53...
Target tumor cells used were K562, Raji, blasts from patients with T-ALL and AML, and PBMCs from the present patient (Pt). O-O, LAK activity; •-•, control cytotoxicity cultured in the absence of IL-2. The effects of T cell antigen-reactive MoAbs on non-MHC-restricted ...
Immunophenotyping of canine large-cell lymphoma (LCL) for B-cell and T-cell surface antigens is commonly performed to better predict the clinical outcome. ... CM Howard,S Anderson,B Harrington - 《Journal of Veterinary Diagnostic Investigation》 被引量: 0发表: 2024年 CD30-positive atypical lym...
Peripheral CD4+ CD8- γδ T cell lymphoma: A case report with multiparameter analyses A 72-year-old Japanese man presented with CD4+ T cell receptor (TCR) γδ T cell lymphoma involving bilateral cervical lymph nodes. No involvement by tumor... R Ichinohasama,I Miura,T Takahashi,... -...
A Case of CD3O-negative Large T-Cell Lymphoma Showing p53 and mdm-2 Expression Primary cutaneous large cell lymphomas of the T-cell phenotype are relatively uncommon. Previous studies have revealed the following prognostic variables: ... SG Kang,YS Ro,CK Park 被引量: 0发表: 1998年 Clarificat...
3 Suzuki Y, Yoshida T, Wang G, et al. Incidence and clinical significance of aberrant T-cell marker expression on diffuse large B-cell lymphoma cells. Acta Haematol 2013;130:230–237. 4 Pan Z, Hu S, Li M, et al. ALK-p...
Impact of Anti-T-lymphocyte globulin dosing on GVHD and Immune reconstitution in matched unrelated myeloablative peripheral blood stem cell transplantation Article Open access 13 July 2022 Reduced CXCR4-expression on CD34-positive blood cells predicts outcomes of persons with primary myelofibrosis Arti...
2月28日,中国国家药监局药品审评中心(CDE)官网公示,阿斯利康(AstraZeneca)申报的1类新药AZD0486获批临床,拟开发治疗复发性或难治性B细胞急性淋巴细胞白血病(r/r B-ALL)。公开资料显示,AZD0486是一款靶向CD19×CD3的双特异性T细胞衔接蛋白(T-Cell Engager,TCE)。2022年7月,阿斯利康以总金额约12.7亿美元TeneoTwo公...
Triple-negative (CD3-/CD4-/CD8-) adult T cell leukemia/lymphoma, histologically presenting as CD30 (Ki-1)-positive anaplastic large cell lymphoma with clon... Kumura, T, Hino, M, Yamane, T (2001) Triple-negative (CD3(−)/CD4(−)/CD8(−)) adult T cell leukemia/lymphoma, histolog...