Effect of Antibody BindingADCP, cytokine releaseADCC, ADCP, vaccinal effectInhibits ADCC, ADCP, B cell activationEnhances ADCC, ADCP, B cell activationADCC, ADCPDecoy receptor that inhibits ADCP 抗体依赖性细胞介导的细胞毒性(ADCC)是一种有效的细胞毒性机制。NK细胞通CD16A (FcγRIIIA)识别细胞结合的抗...
Signal transduction during NK cell activation via CD16: G proteins regulate inositol phosphate generation and ADCC activity.Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical...
Sivori S., Parolini S., Falco M., Marcenaro E., Biassoni R., Bottino C., et al. (2000). 2B4 functions as a co-receptor in human NK cell activation. European Journal of Immunology, 30(3), 787-793. Bryceson Y.T., Fauriat C., Nunes J.M., Wood S.M., Bj?rkstr?m N.K....
CD16 binds aggregated IgG or IgG-antigencomplex which functions in NK cell activation, phagocytosis, and antibody-dependent cellmediated cytotoxicity (ADCC). Verified Reactivity :Human, Cynomolgus, Rhesus Reported Reactivity :African Green, Baboon, Capuchin Monkey, Chimpanzee, Common Marmoset, Pigtailed ...
5.1 NK cell activation via CD16 The Fc receptor CD16 is the only receptor that can activate resting NK cells when stimulated in isolation. CD16 mediates ADCC, which is dependent on antibodies produced by B cells. Therefore, the unwanted activation of resting NK cells through CD16 is still ...
产品类型:NK细胞分选 规格:标记40 mL全血 130-111-553 我要询价 添加 Miltenyi CD56+ CD57+ NK Cell Isolation Kit, human/人CD56+ CD57+NK细胞分离试剂盒 产品类型:NK细胞分选 规格:用于 1×10^9 细胞分选 130-093-395 我要询价 添加 Miltenyi ...
(GPI)-anchored protein. Its extracellular domain is over 95% homologous to that of CD16a, and it is expressed specifically on neutrophils. CD16 binds aggregated IgG or IgG-antigen complex which functions in NK cell activation, phagocytosis, and antibody-dependent cell-mediated cytotoxicity (ADCC)...
NK cellsHIV infectionsInnate lymphoid cellsDegranulation and cytokine production by NK cells in response to the cocrosslinking of CD16 and CD300a. Zebra plots showing the percentage of CD56 NK cells positive for CD107a, IFNγ, MIP-1β, and TNF from a representative untreated HIV-1 infected ...
CD16, the low affinity receptor for monomeric IgG (Fc纬RIIIA), is a well characterized activation molecule on NK cells. In this study we investigated the role of CD16 in NK cell-mediated regulation of immunoglobulin production. Cocultures of the CD16+ human NK clone CNK6 and highly ...
(antibody dependent cell mediated cytotoxicity) by NK cells. IN comparison, CD32 is a 40 kD glycoprotein that acts as a low affinity receptor for IgG (also known as Fc gamma RII), and mediates several functions including endocytosis, activation of secretion, cytotoxicity and immunomodulation. CD...