CD14 和 CD16 表面表达分析:用抗人白细胞抗原(HLA)-DR 藻红蛋白(PE)、抗人 CD14 异硫氰酸荧光素(FITC)和抗人 CD16 藻红蛋白(PE)对新鲜分离的 PBMCs 进行染色。基于细胞大小和复杂性对单核细胞进行设门,在 HLA-DR/CD14 图中排除 HLA-DR 阴性的 NK 细胞,然后分析细胞的 CD14 和 CD16 表达,以确定双...
CD14 +CD16 +单核细胞亚群检测在急性冠脉综合征患者中的应用
CD14+CD16+单核细胞亚群的比例.结果:抗感染治疗前败 血症组 CD14+CD16+单核细胞亚群比例明显高于健康新生儿组(P<0.05);抗 感染治疗后败血症组 CD14+ CD16+单核细胞亚群比例下降,与健康新生儿组之 间差异无统计学意义(P>0.05).结论:对感染新生儿行外周血 CD14+CD16+单 核细胞亚群检测有助于新生儿败血症的...
Chuluundorj D, Harding SA, Abernethy D, La Flamme AC. Expansion and preferential activation of the CD14/CD16 monocyte subset during multiple sclerosis. Immunol Cell Biol 2014; 92:1-9.Chuluundorj, D.; Harding, S.A.; Abernethy, D.; La Flamme, A.C. Expansion and preferential activation ...
Gene Ontology (GO) enrichment analysis suggests diverse immunologic functions, linking CD14++CD16+ monocytes to Ag processing and presentation (eg, CD74, HLA-DR, IFI30, CTSB), to inflammation and monocyte activation (eg, TGFB1, AIF1, PTPN6), and to angiogenesis (eg, TIE2, CD105). In ...
T. (2014). The CD14+CD16+ inflammatory monocyte subset displays increased mito- chondrial activity and effector function during acute Plasmodium vivax malaria. PLoS Pathogens 10, e1004393.Antonelli, L. R., F. M. Leoratti, P. A. Costa, B. C. Rocha, S. Q. Diniz, M. S. Tada, D....
6 During the steady state, CD14hiCD16-subset constitutes the majority of monocytes while CD14+CD16hi subset only presents as a minor subpopulation. The expanding of CD14+CD16hi subset has been reported in system lupus erythematosus,7 rheumatoid arthritis,8 atherosclerosis,9 and HIV-1 infection....
CYNK-101就是由特定类型的免疫细胞 NK 细胞制成,CYNK-101 是一种同种异体、现成的 NK 细胞产品,来源于人胎盘造血干细胞,经过基因修饰以表达高亲和力和抗切割的 CD16 (FCGRIIIA) 抗体来增加NK细胞杀伤活性。 临床前研究表明,加入抗体的新型NK细胞CYNK-101 在体外显示出针对淋巴瘤细胞的...
the M2 marker CD163 in the CD14+low/CD68+low (middle) and CD14+high/CD68+high (right) pMΦ subpopulations (isotype control, ITC; left). Bottom: The CD14+low/CD68+low pMΦ subpopulation has significantly higher levels of the MΦ1 subtype and significantly lower levels of the MΦ2 ...
0102生殖医学科黎俏副主任医师的《合并慢性子宫内膜炎的反复着床失败患者CD56+CD16+自然杀伤细胞水平的研究》、心理科陈子霞主治医师的《首诊青少年抑郁症状与父母养育方式的相关因素研究》分别荣获优秀论文二等奖;生殖医学科成校副主任医师、何韶坚...