Percentages and absolute numbers of CD14++CD16-, CD14++CD16+ and CD14+CD16++ monocyte subsets in studied subjects.Eva, SchepersErica, HouthuysAnnemieke, DhondtGrim, De MeyerNathalie, NeirynckPascale, BernaertRafael, Van den BerghPeter, Brouckaert...
Monocytes represent a heterogeneous population of cells subdivided according to the expression level of membrane antigens. A pro-inflammatory (intermediate/nonclassical) subpopulation of monocytes is defined by expression of CD16. CD163 seems to be chara
immunophenotyping was performed and the absolute count of circulating inflammatory monocytes and of circulating CD14dim/CD16pos/CD45pospatrolling monocytes were measured in another 55 patients
Logistic regression analysis showed that intra-abdominal infection on day 1 was predictive of low CD14dim/ CD16pos/CD45poscount on day 3. Circulating counts of inflammatory and patrolling monocytes are greatly increased in Gram-negative sepsis. Absolute counts of CD14pos/HLA-DRpos/CD45posmonocytes...
Results Compared to HC, total monocyte count was elevated in S/ALF, but reduced in hyperALF (p<0.001), while CD14hi/CD16+ monocytes were expanded in percentage of total monocytes and absolute numbers in S/ALF (17.4%; 0.14) compared to HC (4%; 0.014) (p<0.001). Although the ...