Our previous studies revealed prominent surface CD133 in 90% of the cells of MARY-X, a human xenograft model of inflammatory breast carcinoma (IBC), as well as in 22/25 IBC cases. CD133 is a stem cell marker expressed in some human cancers. Compared to other stem cell molecules, CD133...
CD133作为HSOC表面抗原，在正常以及异常的造血组织和非造血组织中，均有表达，随着细胞的分化，CD133的表达会减弱，甚至是消失。Heo SK等研究表明，AML患者的骨髓中CD133细胞高表达，在分离自AML和慢性髓细系白血病（chronic myeloid leukemia,CML）患者的骨髓培养中显著检测到白血病干细胞（leukemia stem cells,LSC）...
CD133作为HSOC表面抗原,在正常以及异常的造血组织和非造血组织中,均有表达,随着细胞的分化,CD133的表达会减弱,甚至是消失。Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果...
Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果说明AML中的CD133细胞潜在地充当了LSC。 CD11b在白血病的原始细胞、自然杀伤细胞、成熟的单核细胞、粒细胞中表达,分布在骨髓...
2. Xie Xuanhua P,Laks Dan R,Sun Daochun et al. Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence followingchemotherapy.[J] .Dev Cell, 2022, 57: 32-46.e8. 3. Ma Ruichong,Taphoorn Martin J B,Plaha Puneet,Advances in the management of glioblas...
CD133作为HSOC表面抗原,在正常以及异常的造血组织和非造血组织中,均有表达,随着细胞的分化,CD133的表达会减弱,甚至是消失。Heo SK等研究表明,AML患者的骨髓中CD133细胞高表达,在分离自AML和慢性髓细系白血病(chronic myeloid leukemia,CML)患者的骨髓培养中显著检测到白血病干细胞(leukemia stem cells,LSC),研究结果...
研究表明,肿瘤中存在一群与正常干细胞生物学行为和细胞亚群特征相似的细胞,被称为肿瘤干细胞(cancerstemcells,csc),与肿瘤的增殖、转移和复发关系密切。肿瘤干细胞表达特有的干细胞标志物,cd133分子是研究较多的一种,cd133分子是在多种肿瘤干细胞表面均表达的特异标记分子,属于prominin细胞表面蛋白家族。已有研究发现可...
Human prominin-1 (CD133) is expressed by various stem and progenitor cells originating from diverse sources. In addition to stem cells, its mouse ortholog is expressed in a broad range of adult epithelial cells, where it is selectively concentrated in their apical domain. The lack of detection...
[3]Ceils isolated from umbilical cord tissue rescuephotoreceptom and visual functions in a rodent model of retinal disease.Lund RD,Wang S,Lu B,et a.Stem Cells.2007 [4]The multifunctional RNA-binding protein hnRNP A1 is required for processing of miR-18a.S Guil,JF Caceres.Nature Structural...
Stem Cells from Subcutaneous and Visceral Fat Depots[J].Wee Kiat Ong,Chuen Seng Tan,Kai Li Chan,Grace Gandi Goesantoso,Xin Hui Derryn Chan,Edmund Chan,Jocelyn Yin,Chia Rou Yeo,Chin Meng Khoo,Jimmy Bok Yan So,Asim Shabbir,Sue-Anne Toh,Weiping Han,Shigeki Sugii.Stem Cell Reports.2014(2)...