CD122 is the common beta subunit shared by the receptors for interleukins-2 and -15 (IL-2, IL-15), two cytokines implicated in the immunopathogenesis of HTLV-1 associated myelopathy/ tropical spastic paraparesis ( HAM/TSP ). Several in vitro findings suggest that CD122 might be a ...
CD122; IL2R-b; IL2-RB; P70-75; High affinity IL-2 receptor subunit beta; Interleukin-2 receptor subunit beta; IL-2 receptor subunit beta来源:原核表达宿主:E.coli内毒素水平:<1.0EU/µg(LAL法测定)亚细胞定位:n/a预测分子量:26.2kDa实际...
InVivoMAb anti-mouse CD122 (IL-2Rβ)推荐供应商 我要询价 上海优宁维生物科技股份有限公司 联系电话:13774214275 电子邮件:zhouzz@univ-bio.com CB指数:58 网址:www.univ-bio.com/ 相关信息:产品目录(24994)用户评价 公司动态:小优读文献∣Naveni® PLA技术&现有文献部分解析[更多...] ...
基因名: IL2RB 别名: CD122,IL15RB,P70-75 基因ID: 3560 Chromosome:(GRCh37) 22 Start: 37521878 End: 37571094 Strand: -1 信号通路: IL2RB 基因突变与药物 IL2RB-MYH9关于我们 “基因医生”项目,可以为肿瘤患者提供全流程逐级的治疗方案与治疗手段。本项目创始科学家团队在基础医学研究领域拥有丰厚实战经...
对CD122的抗体本发明提供了异性结合CD122的单克隆抗体,而CD122是IL-2和IL-15受体的一个组成部分.通过抑制这些细胞因子与它们的受体结合,所述的单克隆抗体具有实质上抑制IL-2和IL-15介导的功能的能力.所述的单克隆抗体可被用于抑制不希望发生的免疫应答或治疗肿瘤,以及其他.J.·云·曹...
The present invention provides a monoclonal antibody that binds specifically to CD122 is one component of the receptor for IL-15 and IL-2. Monoclonal antibodies, by inhibiting the binding of these cytokines to their receptors, both IL-15 mediated functions with IL-2-mediated function, are ...
The present invention provides a monoclonal antibody that binds specifically to CD122 is one component of the receptor for IL-15 and IL-2. Monoclonal antibodies, by inhibiting the binding of these cytokines to their receptors, both IL-15 mediated functions with IL-2-mediated function, are ...
The homeostasis of CD8CD122 T cell requires IL-15 trans-presentation. We use Il15ra mutant mice and bone marrow chimeras to assess the role of IL-15 trans-presentation level in CD8CD122 T cells homeostasis. We demonstrate that CD8CD122 T cells require different levels of IL-15 trans-...
本发明提供了异性结合CD122的单克隆抗体,而CD122是IL2和IL15受体的一个组成部分. The present invention provides a monoclonal antibody that specifically binds to CD122, and CD122 is a component of IL-2 and IL-15 receptor. 通过抑制这些细胞因子与它们的受体结合,所述的单克隆抗体具有实质上抑制IL2和IL...
Furthermore, CD122 expression was restricted to the earliest B220+ cells (CD43+CD24-; prepro B cells; fraction A) that proliferate vigorously to IL-2 in the absence of any stromal cells, but not to IL-15. Consistent with a role for the IL-2/IL-2R pathway in lymphocyte development ...