2月9日,来自奥地利国家大学的Ian Cockburn团队在Science Immunology发表了研究论文:Zeb2 drives the formation of CD11c atypical B cells which sustain germinal centers that control persistent infection。 首先,作者生成了人扁桃体B细胞的单细胞RNA测序数据集,并筛选出了可能促使ABC分化的高表达TF。为了验证这些转录因...
2月9日,来自奥地利国家大学的Ian Cockburn团队在Science Immunology发表了研究论文:Zeb2 drives the formation of CD11c+ atypical B cells which sustain germinal centers that control persistent infection。 首先,作者生成了人扁桃体B细胞的...
Circulating CD11c B cells, a novel subset of activated B cells, have been linked to autoimmunity and shown to expand with age. Atherosclerosis is an age-associated disease that involves innate and adaptive immune responses to modified self-antigens. Yet, the expression of CD...
近年有研究发现,有一群年龄相关的b细胞(ageassociatedbcells)高表达cd11c,又可称为cd11c+b细胞,到目前为止,国际上没有cd11c+b细胞与脓毒症之间关系的相关报道。 技术实现要素: 针对现有技术缺乏cd11c+b细胞与脓毒症之间关系的相关报道,本研究主要发现cd11c+b细胞在自身免疫性疾病中比例增高,本发明一方面利用cd11c+b...
摘要: CD11c<sup>+</sup> B cells have been reported to be increased in autoimmune diseases, but they are detected in the blood of healthy individuals as well. We aimed to characterize CD11c<sup>+</sup> B cells from healthy donors by flow cytometry, microarray analysis, and关键词:...
Nirmala P,Elisabeth M-H, Gunther B, et al. InfiltratingCD11 b + CD11 c + cells have the potential to mediate induc-ible nitric oxide synthase-dependent cell death in mammarycarcinomas of HER-2/neu transgenic mice[ J] Internation-al Journal of Cancer, 2010,126 :896 -908....
However, the role of CD11c+B cells in the development of lupus is unclear. Chronic graft-versus-host disease (cGVHD) is a lupus-like syndrome with high autoantibody production. The purpose of this study was to explore the role of CD11c+B cells in the pathogenesis of lupus in cGVHD mice....
Reactivity: Human Description CD11c is a 145-150 kD type I transmembrane glycoprotein also known as integrin αXand CR4. CD11c non-covalently associates with integrin β2 (CD18) and is expressed on monocytes/macrophages, dendritic cells, granulocytes, NK cells, and subsets of T and B cells....
CD11cis a type Itransmembrane proteinthat is expressed on monocytes,granulocytes, a subset of B cells, dendritic cells, and macrophages and may be demonstrated on B-cellchronic lymphocytic leukemia,marginal zone lymphomas, andhairy cell leukemia. The amount of this antigen is varied with the antige...
L Swedin,R Arrhigi,B Andersson-Willman,... - 《Particle & Fibre Toxicology》 被引量: 17发表: 2012年 Toxoplasma gondii and the blood-brain barrier. Cells expressing CD11b either with or without CD11c are likely candidate cells for the intracellular transport of T. gondii across the BBB. T...