骨髓来源的抑制性细胞(Myeloid-derived suppressor cells，MDSCs)是骨髓来源的一群异质性细胞，是树突状细胞(dendritic cells，DCs)、巨噬细胞和(或)粒细胞的前体，具有显著抑制免疫细胞应答的能力。小鼠MDSCs的表型为CD11b+Gr-1+，分两个亚型:粒细胞样的MDSCs(CD11b+Ly6C-Ly6G+)和单核细胞样的MDSCs...
与Ly6GhighG-MDSC亚群相比,在所有66个使用的标记物中,只有CXCR4、F4/80、MHC II和CD205在Ly6GlowG-MDSC中高表达(图4C)。此外,对Ly6Glow和Ly6Ghigh的G-MDSC亚群进行分类,通过质谱检测蛋白表达差异(图4D1)。研究发现,与Ly6GlowG-M...
... 请问组织中LY6C+CD11b+LY6G-是什么细胞？ 展开骨髓来源的抑制性细胞(Myeloid-derived suppres洋战x...
为进一步明确具体哪一类免疫细胞参与此过程,作者应用流式细胞技术分析了Ang II灌注的动脉中炎症细胞,结果表明CD45+CD11b+Ly6C+Ly6G-F4/80+巨噬细胞呈现时间依赖性地增加。这些结果提示,骨髓巨噬细胞中CD11b的表达上调可能参与高血压的发生发...
RESEARCH ARTICLE Open AccessCD11b + Ly6C ++ Ly6G - cells show distinct functionin mice with chronic inflammation or tumorburdenEva Källberg, Martin Stenström, David Liberg, Fredrik Ivars and Tomas Leanderson *AbstractBackground: S100A9 has been shown to be important for the function of so ...
在进行细胞表面分子染色前,用CD16/CD32抗体孵育细胞悬液封闭细胞表面的Fc受体。用于检测细胞表面蛋白的抗体包括:购自ebioscience的CD3e、CD4、CD8a、CD19、NK1.1、F4/80、CD45、CD11b、CD45.1、CD45.2、Ki67、Ly6C和购自biolegend的CD115、Ly6G、和Siglec-F。IL4Rα抗体购自R&D。
Expansion of CD11b(þ)Ly6G (þ)Ly6C (int) cells driven by medroxyprogesterone acetate in mice bearing breast tumors restrains NK cell effector functions. Cancer Immunol Immunother 2013; 62:1781-95.Raúl Germán Spallanzani , Tomás Dalotto-Moreno , Ximena Lucía Raffo Iraolagoitia , Andrea ...
To this end, we sorted CD11b+ cells using FACS with regard to the expression of the Ly6G and Ly6C markers into three populations; Ly6C+G+, Ly6C+G- and Ly6C++G-, as shown in Figure 1A. RNA was prepared from the isolated cell populations and S100A9 expression was measured using Q-...
LY6C/G, Rat Anti Mouse Antibody, FITC LY6G Antibody LY6G, Rat Anti Mouse Antibody LY6G Antibody, Biotin LY6G, Rat Anti Mouse Antibody, Biotin LY6G Antibody, FITC LY6G, Rat Anti Mouse Antibody, FITC MBP Antibody Maltose-Binding protein, Mouse Antibody ...